Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer

Table 4 Mean parotid dose in relation to reduction of salivary flow in studies with dose-volume histogram based on planning head and neck computed tomography scans

Study	Patient No	Technique to assess salivary flow	Mean parotid dose	Evaluation time
Teshima et al. [1]	20	Saxon test	30 Gy	NS
Bussels et al. [3]	16	Scintigraphy	22.5 Gy	7 months
Roesink et al. [6]	108	Suction cup	39 Gy	months
Eisbruch et al. [9]	88	Suction cup	26 Gy	12 months
Cerezo et al. [11]	16	Spitting cup	4.7 Gy (contralateral unirradiated parotid)	12 months
Munter et al. [19]	18	Scintigraphy	26 Gy	6 months
Chao et al. [20]	41	Spitting cup	30 Gy	6 months
Saarilahti et al. [21]	17	Spitting cup	25.5 Gy	12 months

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