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Table 3 Multivariate survival analysis (Cox’ proportional hazards regression model) of clinico-pathologic variables and LCN2 expression in patients with endometrial cancer (n = 255)

From: Lipocalin 2 expression is associated with aggressive features of endometrial cancer

Variables

Categories

HRa

95% CIb

P-valuec

LCN2

Negative

1.0

 

0.027

 

Weak/moderate

1.1

0.6-1.9

 
 

Strong

3.9

1.4-10.8

 

Histologic type

Endometrioid

1.0

 

NS

 

Non-endometrioid

1.7

0.9-3.2

 

Histologic grade

Grade 1 and 2

1.0

 

<0.001

 

Grade 3

2.8

1.6-4.9

 

FIGO stage

I/II

1.0

 

<0.001

 

III/IV

8.0

4.8-13.6

 
  1. aAdjusted Hazard ratio, b95% confidence interval, cL ratio test.