Adverse event/ organ system | Patients per NCI CTC grade [n (%)] | |||
---|---|---|---|---|
grade 1 | grade 2 | grade 3 | grade 4 | |
Hematological | ||||
White blood cells | 33 (31) | 22 (20) | 9 (8) | 6 (6) |
Granulocytes | 27 (26) | 16 (15) | 5 (5) | 3 (3) |
Platelets | 16 (15) | 2 (2) | 3 (3) | 1 (1) |
Hemoglobin | 43 (40) | 40 (37) | 3 (3) | 3 (3) |
Fever | 20 (19) | 8 (7) | ||
Non-hematological | ||||
Hair loss | 23 (21) | 79 (73) | ||
Nausea | 53 (49) | 15 (14) | ||
Vomiting | 32 (30) | 10 (9) | ||
Diarrhea | 21 (19) | 8 (7) | 1 (1) | |
Constipation | 18 (17) | 1 (1) | ||
Neurology/Motor | 19 (18) | 6 (6) | 4 (4) | |
Neurology/Sensory | 28 (26) | 16 (15) | 5 (5) | |
Arthralgia | 27 (25) | 9 (8) | 2 (2) | |
Myalgia | 20 (19) | 8 (7) | 3 (3) | |
Lung function | 11 (10) | 8 (7) | 2 (2) | 3 (3) |
Pain | 21 (19) | 28 (26) | 8 (7) |