Skip to main content

Table 1 Definition of risk categories for breast cancer patients who had undergone surgery, according to the 2005 St. Gallen guidelines

From: A comparison of survival outcomes and side effects of toremifene or tamoxifen therapy in premenopausal estrogen and progesterone receptor positive breast cancer patients: a retrospective cohort study

Risk Category Patient Features
Low risk Node negative AND all of the following features:
pT ≤2 cm,
Grade 1,
Absence of peritumoral vascular invasion,
HER2/neu gene neither overexpressed nor amplified,
Age ≥35 years
Intermediate risk Node negative AND at least one of the following features:
pT >2 cm,
Grade 2–3,
Presence of peritumoral vascular invasion,
HER2/neu gene overexpressed or amplified,
Age >35 years
Node positive (1–3 involved nodes) AND
HER2/neu gene neither overexpressed nor amplified
High risk Node positive (1–3 involved nodes) AND
HER2/neu gene overexpressed or amplified
Node positive (4 or more involved nodes)