From: Body mass index and survival after breast cancer diagnosis in Japanese women
 | BMI | Patients | Person-years | Breast cancer- specific death | Age-adjusted |  | Multivariate-adjusted |  | |||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  |  |  |  | HR | 95% CI |  | HR | 95% CI |  |
All | |||||||||||
 |  | <21.2 | 163 | 963.0 | 34 | 1.69 | 0.98 - 2.92 |  | 1.59 | 0.90 - 2.81 |  |
 |  | ≥21.2 to <23.3 | 166 | 1052.4 | 21 | 1.00 (reference) | 1.00 (reference) a | ||||
 |  | ≥23.3 to <25.8 | 161 | 1020.1 | 26 | 1.32 | 0.74 - 2.35 |  | 1.20 | 0.66 - 2.17 |  |
 |  | ≥25.8 | 163 | 997.3 | 27 | 1.40 | 0.79 - 2.49 |  | 1.46 | 0.81 - 2.64 |  |
 | p for trend |  |  | 0.64 |  |  | 0.87 | ||||
 | p for trend in women with BMI ≥21.2 |  |  | 0.20 |  |  | 0.18 | ||||
Premenopausal | |||||||||||
 |  | <21.2 | 89 | 556.1 | 15 | 1.60 | 0.68 - 3.80 |  | 1.22 | 0.47 - 3.14 |  |
 |  | ≥21.2 to <23.3 | 73 | 510.2 | 8 | 1.00 (reference) |  | 1.00 (reference) b |  | ||
 |  | ≥23.3 to <25.8 | 63 | 391.6 | 11 | 1.77 | 0.71 - 4.41 |  | 1.62 | 0.63 - 4.20 |  |
 |  | ≥25.8 | 52 | 319.8 | 10 | 1.95 | 0.77 - 4.96 |  | 1.68 | 0.61 - 4.65 |  |
 | p for trend |  |  | 0.48 |  |  | 0.34 | ||||
 | p for trend in women with BMI ≥21.2 |  |  | 0.18 |  |  | 0.51 | ||||
Postmenopausal | |||||||||||
 |  | <21.2 | 67 | 371.6 | 15 | 1.89 | 0.87 - 4.11 |  | 1.22 | 0.52 - 2.86 |  |
 |  | ≥21.2 to <23.3 | 86 | 500.7 | 11 | 1.00 (reference) |  | 1.00 (reference) b |  | ||
 |  | ≥23.3 to <25.8 | 93 | 589.2 | 13 | 1.09 | 0.49 - 2.45 |  | 0.79 | 0.32 - 1.93 |  |
 |  | ≥25.8 | 108 | 670.7 | 14 | 1.02 | 0.46 - 2.26 |  | 1.03 | 0.43 - 2.50 |  |
 | p for trend |  |  | 0.15 |  |  | 0.56 | ||||
 | p for trend in women with BMI ≥21.2 |  |  | 0.86 |  |  | 0.45 | ||||
Pre v Post p for heterogeneity of trends | Â | Â | 0.13 | Â | Â | 0.27 | |||||
Pre v Post p for heterogeneity of trends in women with BMI ≥21.2 |  | 0.29 |  |  | 0.80 |