Table 3 Univariate analysis of prognostic factors in term of overall survival and HCC-specific overall survival
Characteristic | HCC-specific overall survival rate (%) | Overall survival rate (%) | ||||
|---|---|---|---|---|---|---|
3y | 5y | Pvalue | 3y | 5y | Pvalue | |
Gender | 0.901 | 0.815 | ||||
Female (n = 7) | 45.5 | 38.4 | 85.7 | 64.3 | ||
Male (n = 61) | 51.4 | 34.3 | 58.0 | 50.4 | ||
Age (years)* | 0.441 | 0.612 | ||||
< 58 (n = 33) | 52.3 | 47.1 | 62.7 | 62.7 | ||
≥58 (n = 35) | 40.5 | 27.1 | 59.8 | 41.7 | ||
HBsAg status | 0.148 | 0.909 | ||||
Negative (n = 23) | 40.0 | 28.6 | 56.0 | 49.1 | ||
Positive (n = 45) | 50.8 | 36.2 | 62.4 | 51.8 | ||
AFP (ug/l) | 0.034 | 0.252 | ||||
≤ 25 (n = 30) | 62.9 | 48.4 | 68.9 | 68.9 | ||
>25 (n = 38) | 32.6 | 27.2 | 54.9 | 39.6 | ||
GGT level (u/l) | 0.040 | 0.073 | ||||
≤ 50 (n = 23) | 71.8 | 71.8 | 76.5 | 76.5 | ||
> 50 (n = 45) | 35.9 | 29.4 | 52.9 | 43.8 | ||
Cirrhosis | .255 | 0.078 | ||||
No (n = 17) | 65.8 | 65.8 | 85.6 | 66.3 | ||
Yes (n = 51) | 40.9 | 29.5 | 52.9 | 46.8 | ||
Child-Pugh classification | 0.334 | 0.083 | ||||
A (n = 49) | 50.8 | 39.7 | 64.6 | 59.8 | ||
B (n = 19) | 36.4 | 27.3 | 48.2 | 32.8 | ||
Tumor size (cm) | 0.865 | 0.537 | ||||
≤5 (n = 28) | 49.0 | 42.0 | 62.8 | 47.3 | ||
>5 (n = 40) | 44.6 | 31.5 | 59.7 | 48.0 | ||
Multiple tumors | 0.001 | 0.221 | ||||
No (n = 49) | 58.0 | 48.1 | 65.3 | 57.7 | ||
Yes (n = 19) | 11.1 | 11.1 | 62.1 | 41.4 | ||
Vascular invasion | 0.001 | 0.977 | ||||
No (n = 58) | 51.7 | 40.2 | 60.2 | 52.3 | ||
Yes (n = 10) | 0 | 0 | 66.8 | 53.4 | ||
TNM stage | <0.001 | 0.698 | ||||
I (n = 43) | 58.4 | 50.0 | 61.4 | 54.0 | ||
II/III (n = 25) | 17.1 | 0 | 60.1 | 47.7 | ||
Time of appearance | 0.360 | 0.008 | ||||
Synchronous (n = 22) | 34.5 | 23.0 | 25.7 | 25.7 | ||
Metachronous (n = 46) | 50.3 | 40.3 | 72.8 | 61.3 | ||
Treatment for HCC | <0.001† | 0.160 | ||||
Resection (n = 35) | 71.9 | 52.0 | 64.9 | 64.9 | ||
Ablation (n = 8) | 50.8 | 50.8 | 66.7 | 50.0 | ||
TACE (n = 14) | 0 | 0 | 50.0 | 37.6 | ||
Supportive (n = 11) | 0 | 0 | 40.0 | 26.7 | ||
Treatment for EHPM | 0.067 | <0.001‡ | ||||
Curative (n = 54) | 47.3 | 33.2 | 72.4 | 63.4 | ||
Palliative (n = 8) | 19.2 | 19.2 | 35.7 | 17.9 | ||
Supportive (n = 6) | 11.7 | 11.7 | 0 | 0 | ||