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Table 2 Patient demographical characteristics of 68 multiple primary patients with hepatocellular carcinoma

From: Clinical features and outcome of multiple primary malignancies involving hepatocellular carcinoma: A long-term follow-up study

Characteristic

Total

Synchronous group (n = 22)

Metachronous group (n = 46)

Pvalue *

Age (years)

    

  < 58 b

33

8

25

0.165

  ≥ 58

35

14

21

 

Gender

   

0.514

  Male

61

21

40

 

  Female

7

1

6

 

HBsAg status

   

0.393

  Negative

23

9

14

 

  Positive

45

13

32

 

Serum AFP level (ng/ml)

   

0.085

  < 25

30

13

17

 

  ≥ 25

38

9

29

 

Serum GGT level (U/ml)

   

0.181

  < 50

23

5

18

 

  ≥ 50

45

17

28

 

Child-Pugh classification

   

0.932

  A

49

16

33

 

  B

19

6

13

 

TNM stage

   

0.735

  I

43

14

29

 

  II

9

2

7

 

  III

16

6

10

 

Treatment for HCC

   

0.309

  Resection

35

9

26

 

  Ablation

7

3

4

 

  TACE

14

4

10

 

  Supportive

11

6

5

 

Treatment for extrahepatic cancer

  

<0.001

  Curative

54

12

42

 

  Palliative

8

4

4

 

  Supportive

6

6

0

 
  1. HCC hepatocellular carcinoma, HbsAg Hepatitis B surface Antigen, AFP α-fetoprotein, GGT gamma-glutamyltransferase, TNM tumor-node-metastasis, TACE transarterial chemoembolization.
  2. * Chi-square or Fisher’s exact test.
  3. Patients were divided according to the median age.