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Table 1 Effect of drug combinations on SKOV-3 cell viability

From: Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C

Cell Viability

[% of Untreated Control]

DOX

[10 μM]

MMC

[10 μM]

4-HPR

[5 μM]

5-FU

[1 mM]

No TM

70.7%

73.0%

83.1%

78.3%

With TM, 30 μM

20.9%

48.2%

40.3%

48.2%

Cytotoxicity Increase

2.5 fold

1.6 fold

2.9 fold

1.9 fold