Table 1 Correlation between HOXA1 immunoexpression and clinicopathological variables of 127 OSCCs
Parameter | % of positive cells | p value | |
|---|---|---|---|
|  | < 37 | ≥ 37 |  |
| Â | n (%) | n (%) | Â |
Age | Â | Â | Â |
< 56 years | 37 (48.68) | 26 (50.98) | 0.79 |
≥ 56 years | 39 (51.32) | 25 (49.02) |  |
Gender | Â | Â | Â |
Male | 60 (78.94) | 43 (84.31) | 0.44 |
Female | 16 (21.06) | 8 (15.69) | Â |
Ethnicity | Â | Â | Â |
Caucasian | 64 (84.21) | 44 (86.27) | 0.75 |
Non-Caucasian | 12 (15.79) | 7 (13.73) | Â |
Smoking habit | Â | Â | Â |
No | 8 (10.52) | 4 (7.84) | 0.61 |
Yes | 68 (89.48) | 47 (92.16) | Â |
Drinking habit | Â | Â | Â |
No | 14 (18.42) | 13 (25.49) | 0.34 |
Yes | 62 (81.58) | 38 (74.51) | Â |
Location | Â | Â | Â |
Tongue | 53 (69.73) | 38 (74.5) | 0.55 |
Other | 23 (30.27) | 13 (25.5) | Â |
T Stage | Â | Â | Â |
T1 + T2 | 33 (43.42) | 13 (25.49) | 0.039 |
T3 + T4 | 43 (56.58) | 38 (74.51) | Â |
N Stage | Â | Â | Â |
N0 | 45 (59.21) | 21 (41.17) | 0.046 |
N+ | 31 (40.79) | 30 (58.83) | Â |
Histopathological grade | Â | Â | Â |
WD + MD | 48 (63.15) | 22 (43.13) | 0.026 |
Undifferentiated | 28 (36.85) | 29 (56.87) | Â |
Vascular infiltration | Â | Â | Â |
No | 48 (63.16) | 33 (64.7) | 0.85 |
Yes | 28 (36.84) | 18 (35.3) | Â |
Neural Infiltration | Â | Â | Â |
No | 44 (57.89) | 36 (70.58) | 0.14 |
Yes | 32 (42.11) | 15 (29.42) | Â |
Ki-67 positive cells | Â | Â | Â |
< 23% | 56 (73.68) | 14 (27.45) | 0.0001 |
≥ 23% | 20 (26.32) | 37 (72.55) |  |