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Table 2 Correlations between ALCAM expression and clinicopathological factors

From: Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients

    ALCAM expression  
   All patients negative (IRS 0-1) positive (IRS 2-12) p-value
All samples   233 97 136  
Histological subtype (n = 233) squamous 171 70 101  
  adenomatous 35 18 17  
  adenosquamous 27 9 18 0.338
FIGO stage (n = 233) I 143 60 83  
  II 65 25 40  
  III/IV 25 12 13 0.971
Nodal involvement (n = 233) pN0 175 75 100  
  pN1 58 22 36 0.542
Number of Positive lymph nodes (n = 233) 0 175 75 100  
  1-3 39 12 27  
  > 3 19 10 9 0.229
Tumor grade (n = 227) G1 9 4 5  
  G2 100 43 57  
  G3 118 46 72 0.788
Lymphatic invasion (n = 207) L0 68 33 35  
  L1 139 55 84 0.234
Invasion depth in mm (n = 195) geometric mean 14.2 14.3 (n = 90) 14.1 (n = 105) 0.856
Patients age in years (n = 233) mean 48.8 48.3 49.1 0.662
SCC-Ag in μg/L (n = 156) geometric mean 1.9 2.5 (n = 64) 1.5 (n = 92) 0.012
s-ALCAM in ng/mL (n = 55) geometric mean 28.3 29.0 (n = 21) 27.8 (n = 34) 0.515
Progression-free survival in months (PFS; n = 47) median 13 9 (n = 19) 15 (n = 28) 0.208