Table 3 Genealogical Index of Familiality for cancers with at least 200 cases with genealogy data, ranked by empirical significance for overall excess relatedness (and ranked by case GIF where the overall empirical significance values are equivalent)

Chronic Lymphocytic Leukemia

978

7.90

4.76

5.10

4.14

0.26

0.20

< 0.0001

< 0.0001

Small Intestine

387

7.49

4.67

4.56

4.12

0.53

0.38

< 0.0001

0.137

Lip

1077

7.26

4.83

4.89

4.14

0.25

0.20

< 0.0001

0.0001

Thyroid

1865

6.38

4.49

4.48

4.07

0.13

0.11

< 0.0001

0.0006

Testis

691

5.97

4.37

4.18

4.01

0.26

0.20

< 0.0001

0.1943

Multiple Myeloma

1268

5.90

4.76

4.59

4.14

0.21

0.17

< 0.0001

0.0067

Prostate

18069

5.57

4.76

4.44

4.15

0.03

0.03

< 0.0001

< 0.0001

Melanoma

4463

5.56

4.57

4.53

4.11

0.08

0.07

< 0.0001

< 0.0001

Colon

6285

5.49

4.78

4.26

4.13

0.07

0.06

< 0.0001

0.0233

Lung/Bronchus

5063

5.42

4.75

4.27

4.14

0.08

0.07

< 0.0001

0.046

Rectum

2472

5.38

4.73

4.34

4.13

0.13

0.11

< 0.0001

0.032

Kidney

1791

5.35

4.65

4.36

4.12

0.15

0.13

< 0.0001

0.035

Ovary

1941

5.32

4.68

4.27

4.11

0.14

0.12

< 0.0001

0.1042

Non Hodgkin Lymphoma

3267

5.26

4.65

4.44

4.12

0.10

0.08

< 0.0001

0.0002

Breast

12523

5.10

4.70

4.16

4.12

0.04

0.04

< 0.0001

0.2009

Stomach

1490

5.66

4.86

4.32

4.16

0.19

0.16

0.0001

0.1553

Pancreas

1893

5.45

4.77

4.32

4.13

0.16

0.13

0.0001

0.0757

Bladder

2455

5.29

4.84

4.15

4.14

0.13

0.11

0.0008

0.4479

Hodgkin Lymphoma

752

5.25

4.44

3.88

4.03

0.26

0.20

0.0018

0.7628

Endometrial

3155

5.04

4.72

4.03

4.12

0.11

0.09

0.002

0.8261

Cervix

922

5.35

4.68

4.20

4.12

0.26

0.20

0.007

0.3315

Larynx

427

6.06

4.76

4.41

4.14

0.52

0.38

0.0121

0.2366

Brain

1488

4.83

4.45

4.03

4.03

0.16

0.13

0.0124

0.5067

Anus

396

6.33

4.98

4.81

4.17

0.62

0.43

0.0226

0.079

Genital Female

365

6.01

4.75

4.32

4.12

0.60

0.43

0.0266

0.3117

Salivary

338

5.95

4.68

4.52

4.13

0.61

0.44

0.0286

0.1808

Liver/Hepatic

449

5.50

4.63

4.32

4.10

0.47

0.34

0.0418

0.253

Pharynx

315

5.82

4.64

3.30

4.10

0.65

0.46

0.0447

0.9682

Acute Myelogenous Leukemia

920

5.01

4.62

3.84

4.09

0.25

0.19

0.0651

0.8933

Tongue

347

5.57

4.65

3.49

4.13

0.58

0.42

0.0686

0.9418

Acute Lymphocytic Leukemia

409

4.58

4.14

3.98

3.83

0.38

0.27

0.1284

0.2822

Gallbladder

306

5.49

4.90

4.15

4.15

0.77

0.53

0.2106

0.4799

Esophagus

520

4.83

4.71

3.90

4.15

0.42

0.31

0.3814

0.7854

Chronic Myelogenous Leukemia

343

4.59

4.69

4.16

4.10

0.61

0.44

0.5345

0.4319

Oropharynx

261

4.48

4.68

3.37

4.13

0.77

0.54

0.5686

0.9274

Bone

294

3.66

4.34

3.66

3.97

0.56

0.40

0.9014

0.7829