Table 3 Correlation of CD4+ and FOXP3+ TILs with hormone receptor and her2/neu status in ductal carcinomas
Compartment/TIL subtype | ER status | PR status | Her2/neu | ||||||
|---|---|---|---|---|---|---|---|---|---|
- | + | p-value | - | + | p-value | - | + | p-value | |
Total | |||||||||
CD4 + | 25.1 ± 29.7 | 15.6 ± 22.9 | < 0.001 | 12.4 ± 19.3 | 17.9 ± 25.2 | 0.008 | 17.0 ± 24.5 | 22.4 ± 27.4 | 0.023 |
FOXP3 + | 11.9 ± 16.1 | 6.9 ± 11.3 | < 0.001 | 8.6 ± 13.4 | 6.7 ± 10.9 | 0.203 | 7.6 ± 12.6 | 10.6 ± 13.0 | < 0.001 |
Intratumoral | |||||||||
CD4 + | 17.5 ± 23.4 | 10.7 ± 18.5 | < 0.001 | 8.2 ± 13.6 | 12.7 ± 21.6 | 0.032 | 11.7 ± 19.7 | 15.6 ± 21.8 | 0.036 |
FOXP3 + | 7.0 ± 12.8 | 3.0 ± 7.0 | < 0.001 | 4.0 ± 9.2 | 2.7 ± 6.1 | 0.12 | 3.7 ± 8.7 | 4.7 ± 8.1 | 0.009 |