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Table 2 Correlation of CD4+ and FOXP3+ TILs and B.R.E. grade of ductal carcinomas

From: Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+tumor infiltrating lymphocytes in ductal and lobular breast cancers

  Ductal carcinoma  
Compartment/TIL subtype B.R.E. grade  
  1 2 3 p-value*
Total     
CD4 + 10.9 ± 21.2 18.0 ± 24.3 21.2 ± 26.2 < 0.001
FOXP3 + 4.8 ± 10.7 7.0 ± 11.4 11.2 ± 15.6 < 0.001
Intratumoral     
CD4 + 7.5 ± 17.2 12.3 ± 20.1 14.8 ± 20.2 < 0.001
FOXP3 + 1.8 ± 5.8 3.1 ± 7.2 6.1 ± 11.8 < 0.001
  1. Mean ± SD, counts of immunoreactive lymphocytes CD4+ and FOXP3+ Wilcoxon Rank Sum Test; *after adjustment for multiple comparisons, only p < 0.001 was considered statistically significant
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