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Table 2 Correlation of CD4+ and FOXP3+ TILs and B.R.E. grade of ductal carcinomas

From: Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+tumor infiltrating lymphocytes in ductal and lobular breast cancers

 

Ductal carcinoma

 

Compartment/TIL subtype

B.R.E. grade

 
 

1

2

3

p-value*

Total

    

CD4 +

10.9 ± 21.2

18.0 ± 24.3

21.2 ± 26.2

< 0.001

FOXP3 +

4.8 ± 10.7

7.0 ± 11.4

11.2 ± 15.6

< 0.001

Intratumoral

    

CD4 +

7.5 ± 17.2

12.3 ± 20.1

14.8 ± 20.2

< 0.001

FOXP3 +

1.8 ± 5.8

3.1 ± 7.2

6.1 ± 11.8

< 0.001

  1. Mean ± SD, counts of immunoreactive lymphocytes CD4+ and FOXP3+ Wilcoxon Rank Sum Test; *after adjustment for multiple comparisons, only p < 0.001 was considered statistically significant
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BMC Cancer

ISSN: 1471-2407

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