From: Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients
STS patients | OPN splice variant | n | Median values [copies OPN splice variant mRNA/ copies HPRT mRNA] | Kaplan-Meier analysis | multivariate Cox's regression model | |||
---|---|---|---|---|---|---|---|---|
Survival [months] | P | RR | P | CI | ||||
All | OPN-a low | 62 | 0.68 | 90 | ||||
OPN-a high | 62 | 71 | 1.7 | 1.7 | 0.06 | 1.0-3.0 | ||
OPN-b low | 62 | 0.49 | 117 | |||||
OPN-b high | 62 | 66 | 0.13 | 2.1 | 0.02 | 1.2-3.6 | ||
OPN-c low | 62 | 0.08 | 94 | |||||
OPN-c high | 62 | 81 | 0.38 | 1.8 | 0.04 | 1.0-3.1 | ||
Female | OPN-a low | 34 | 0.83 | 116 | ||||
OPN-a high | 34 | 53 | 0.08 | 3.0 | 0.01 | 1.3-6.8 | ||
OPN-b low | 34 | 0.58 | 102 | |||||
OPN-b high | 34 | 42 | 0.13 | 3.4 | < 0.01 | 1.4-8.2 | ||
OPN-c low | 34 | 0.09 | 92 | |||||
OPN-c high | 34 | 46 | 0.50 | 2.3 | 0.07 | 0.9-5.4 | ||
RT patients | OPN-a low | 26 | 0.65 | 80 | ||||
OPN-a high | 26 | 76 | 0.04 | 3.5 | 0.07 | 0.9-13.0 | ||
OPN-b low | 26 | 0.42 | 147 | |||||
OPN-b high | 26 | 55 | 0.05 | 10.3 | < 0.01 | 2.0-53.7 | ||
OPN-c low | 26 | 0.07 | 147 | |||||
OPN-c high | 26 | 55 | 0.05 | 11.4 | < 0.01 | 2.2-59.3 |