Skip to main content

Table 3 Kaplan-Meier analyses and multivariate Cox's regression analyses

From: Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients

STS patients

OPN splice variant

n

Median values

[copies OPN splice

variant mRNA/

copies HPRT mRNA]

Kaplan-Meier analysis

multivariate Cox's regression model

    

Survival [months]

P

RR

P

CI

All

OPN-a low

62

0.68

90

    
 

OPN-a high

62

 

71

1.7

1.7

0.06

1.0-3.0

 

OPN-b low

62

0.49

117

    
 

OPN-b high

62

 

66

0.13

2.1

0.02

1.2-3.6

 

OPN-c low

62

0.08

94

    
 

OPN-c high

62

 

81

0.38

1.8

0.04

1.0-3.1

Female

OPN-a low

34

0.83

116

    
 

OPN-a high

34

 

53

0.08

3.0

0.01

1.3-6.8

 

OPN-b low

34

0.58

102

    
 

OPN-b high

34

 

42

0.13

3.4

< 0.01

1.4-8.2

 

OPN-c low

34

0.09

92

    
 

OPN-c high

34

 

46

0.50

2.3

0.07

0.9-5.4

RT patients

OPN-a low

26

0.65

80

    
 

OPN-a high

26

 

76

0.04

3.5

0.07

0.9-13.0

 

OPN-b low

26

0.42

147

    
 

OPN-b high

26

 

55

0.05

10.3

< 0.01

2.0-53.7

 

OPN-c low

26

0.07

147

    
 

OPN-c high

26

 

55

0.05

11.4

< 0.01

2.2-59.3

  1. Association of the mRNA expression of OPN splice variants in different groups of patients (all STS patients, females and RT patients) with overall survival. The median values of OPN-a, OPN-b and OPN-c were used as cut-off points to divide the STS patients into two groups: one with high and one with low (reference group) OPN mRNA levels in tumor tissues