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Figure 5 | BMC Cancer

Figure 5

From: Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1in tumors of epithelial, NK- and B-cell origins

Figure 5

(A-D) Pharmacologic demethylation with 5-aza-dC at indicated concentrations and time points analyzed by MSP in Rael, NK-YS and C666-1 cell lines. Each bottom panel is the plotted densitometry ratios as % of methylation (U/U + M) of Zp and Rp. M, methylated; U, unmethylated. (E, F). Detailed BGS analysis of demethylation after 5-aza-dC treatment in Rael and C666-1 cell lines. "x" circle, CpG site abolished by sequence variation or undetermined methylation status due to an unconverted C in nearby CpN site.

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BMC Cancer

ISSN: 1471-2407

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