Figure 4

(A, B) Methylation profiling of Zp and Rp of multiple EBV-associated tumors. NPC, nasopharyngeal carcinoma; BL, Burkitt lymphoma; PTLD, posttransplant lymphoproliferative disease. Circles, CpG sites analyzed; row of circles, an individual promoter allele sequenced; Filled circle, methylated; empty circle, unmethylated. "x" circle, CpG site abolished by sequence variation or undetermined methylation status due to unconverted C in nearby CpN site.