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Table 6 KRAS genotype frequencies and histopathologic grade components among HRT users

From: KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control study

Histopathologic grade components

Genotype

Frequency

p value

  

N(%)

 
  

1/2

3

 

Tubular formation

wild(TT)

54(87.1)

75(83.3)

0.525

 

variable(TG/GG)

8(12.9)

15(16.7)

 

Nuclearatypia

wild(TT)

82(91.1)

47(75.8)

0.010

 

variable(TG/GG)

8(8.9)

15(24.2)

 

Mitoticindex

wild(TT)

102(90.3)

27(71.1)

0.004

 

variable(TG/GG)

11(9.7)

11(28.9)

 
  1. Statistically significant results are shown in bold