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Table 6 KRAS genotype frequencies and histopathologic grade components among HRT users

From: KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control study

Histopathologic grade components Genotype Frequency p value
   N(%)  
   1/2 3  
Tubular formation wild(TT) 54(87.1) 75(83.3) 0.525
  variable(TG/GG) 8(12.9) 15(16.7)  
Nuclearatypia wild(TT) 82(91.1) 47(75.8) 0.010
  variable(TG/GG) 8(8.9) 15(24.2)  
Mitoticindex wild(TT) 102(90.3) 27(71.1) 0.004
  variable(TG/GG) 11(9.7) 11(28.9)  
  1. Statistically significant results are shown in bold