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Table 5 KRAS genotype frequencies and histopathologic grade according to HRT stratification

From: KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control study

Study population Genotype Frequency p value
   N(%)  
   1/2 3  
All wild(TT) 261(84.2) 165(80.5) 0.276
  variable(TG/GG) 49(15.8) 40(19.5)  
Nonusers: HRT < 1 year wild(TT) 167(81.1) 130(83.3) 0.578
  variable(TG/GG) 39(18.9) 26(16.7)  
Users: HRT 1 years wild(TT) 94(90.4) 35(71.4) 0.003
  variable(TG/GG) 10(9.6) 14 (28.6)  
  1. Statistically significant results are shown in bold