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Table 5 KRAS genotype frequencies and histopathologic grade according to HRT stratification

From: KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control study

Study population

Genotype

Frequency

p value

  

N(%)

 
  

1/2

3

 

All

wild(TT)

261(84.2)

165(80.5)

0.276

 

variable(TG/GG)

49(15.8)

40(19.5)

 

Nonusers: HRT < 1 year

wild(TT)

167(81.1)

130(83.3)

0.578

 

variable(TG/GG)

39(18.9)

26(16.7)

 

Users: HRT 1 years

wild(TT)

94(90.4)

35(71.4)

0.003

 

variable(TG/GG)

10(9.6)

14 (28.6)

 
  1. Statistically significant results are shown in bold