Figure 7
Expression of markers for epithelial and mesenchymal lineages in metastatic lesions of lung and liver. A-B. IHC performed on 5 μm paraffin-embedded sections of a lung and liver using a monoclonal anti-human antibody to E-cadherin. C-D. IHC performed on 5 μm paraffin-embedded sections of a lung and liver using a polyclonal anti-human antibody to β-catenin. E-F. IHC performed on 5 μm paraffin-embedded sections of a lung and liver using a polyclonal anti-human antibody to fibronectin. G-H. IHC performed on 5 μm paraffin-embedded sections of a lung and liver using a monoclonal anti-human antibody to ERα. G. Inset panel (bottom left) demonstrates negative staining in normal lung cells in proximity to the metastatic lesion in the lung. 200× magnification in all panels.