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Figure 2 | BMC Cancer

Figure 2

From: Resveratrol protects leukemic cells against cytotoxicity induced by proteasome inhibitors via induction of FOXO1 and p27Kip1

Figure 2

Protective roles of resveratrol against proteasome inhibition in a panel of leukemic cells. A, K562 cells were treated with 5 nM PSI, 10 μM lactacystin or 50 nM epoxomicin alone or combination with 5 μM resveratrol for 24 h. Apoptotic cells were analyzed using Annexin-FITC/PI double staining followed by FACS analysis. B, A panel of leukemic cells was treated with 5 μM MG132 alone or combination with 5 μM resveratrol for 24 h, and apoptotic cells were analyzed using Annexin-FITC/PI double staining followed by FACS analysis. The results are presented as mean of three independent experiments performed in triplicate, and error bars represent standard deviation. *, P < 0.05; **, P < 0.01.

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