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Table 2 Acute adverse events that occurred during preoperative chemoradiotherapy

From: Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer

 

Number of patients (%)

N = 85

Adverse event

Grade 3

Grade 4

Diarrhea

14 (17)

4 (5)

Nausea/vomiting

4 (5)

1 (1)

Cerebrovascular event

0

2 (2)

Proctitis

1 (1)

0

Radiocystitis

1 (1)

0

Radiodermatitis

2 (2)

0

Anemia

1 (1)

0

Leukopenia

0

1 (1)

Neutropenia

0

1 (1)

Hand-foot syndrome

0

0

Mucositis

1 (1)

0

Subocclusive syndrome

1 (1)

0

Second-degree cutaneous burns*

1 (1)

0

Epistaxis

1 (1)

0

Pneumopathy

1 (1)

0

Thrombophlebitis

1 (1)

0

Total

29 (34)

8 (9)

  1. 1. *Not related to treatment