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Table 2 Hazard ratios for OS and PFS of 183 patients with EOC after univariate COX regression analysis of CXCL12 abundance and clinical and pathologic features

From: CXCL12 expression by healthy and malignant ovarian epithelial cells

  Overall survival Progression-free survival
  HRa[95% CIb] Pvalue HR [95% CI] Pvalue
CXCL12 (5-7)
vs (0-4)
0.80 [0.51-1.28] 0.36 0.91 [0.65-1.29] 0.62
HER2
Positive vs negative
1.41 [0.68-2.90] 0.36 1.45 [0.84-2.51] 0.18
Age
>60 vs ≤60 years
1.40 [0.99-1.97] <0.057 1.17 [0.90-1.51] 0.22
Performance status
1+2 vs 0
1.72 [1.20-2.48] <0.003 1.45 [1.11-1.88] <0.005
FIGO stage
III+IV vs I+II
5.55 [2.27-13.60] <0.0002 4.43 [2.65-7.39] <0.0001
Ascites
Presence vs absence
3.33 [2.16-5.14] <0.0001 2.29 [1.71-3.05] <0.0001
Residual tumor after initial laparotomy
>1 cm vs ≤1 cm
1.72 [1.03-2.88] <0.04 1.97 [1.36-2.87] <0.0004
  1. aHazard ratio. b95% confidence interval.