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Table 2 Hazard ratios for OS and PFS of 183 patients with EOC after univariate COX regression analysis of CXCL12 abundance and clinical and pathologic features

From: CXCL12 expression by healthy and malignant ovarian epithelial cells

 

Overall survival

Progression-free survival

 

HRa[95% CIb]

Pvalue

HR [95% CI]

Pvalue

CXCL12 (5-7)

vs (0-4)

0.80 [0.51-1.28]

0.36

0.91 [0.65-1.29]

0.62

HER2

Positive vs negative

1.41 [0.68-2.90]

0.36

1.45 [0.84-2.51]

0.18

Age

>60 vs ≤60 years

1.40 [0.99-1.97]

<0.057

1.17 [0.90-1.51]

0.22

Performance status

1+2 vs 0

1.72 [1.20-2.48]

<0.003

1.45 [1.11-1.88]

<0.005

FIGO stage

III+IV vs I+II

5.55 [2.27-13.60]

<0.0002

4.43 [2.65-7.39]

<0.0001

Ascites

Presence vs absence

3.33 [2.16-5.14]

<0.0001

2.29 [1.71-3.05]

<0.0001

Residual tumor after initial laparotomy

>1 cm vs ≤1 cm

1.72 [1.03-2.88]

<0.04

1.97 [1.36-2.87]

<0.0004

  1. aHazard ratio. b95% confidence interval.