From: Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer
Symbol | Gene name | Cytoband | Difference in expression (log2 mutant - wild type) | P value |
---|---|---|---|---|
RGS2 | Regulator of G-protein signaling 2, 24kDa | 1q31 | 1.99 | 5.9 E-3 |
NCAM1 | Neural cell adhesion molecule 1 | 11 ( multiple clusters) | -1.63 | 1.5 E-3 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 1q32 | 1.49 | 6.9 E-4 |
PTGS2/COX-2 | Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)/Cyclooxygenase-2 | 1q25.2-q25.3 | 1.32 | 3.1 E-3 |
ECM1 | Extracellular matrix protein 1 | 1q21 | 1.21 | 5.9 E-3 |
EXTL2 | Exostoses (multiple)-like 2 | 1p21 | -1.08 | 4.2 E-3 |
HIST2H2BE | Histone cluster 2, H2be | 1q21-q23 | 1.07 | 2.7 E-3 |
H2AA | Histone 2 | 1q21 | 0.95 | 1.2 E-3 |
CHEK1 | CHK1 checkpoint homolog (S. pombe) | 11q24-q24 | -0.94 | 6.1 E-3 |
GPX7 | Glutathione peroxidase 7 | 1p32 | -0.88 | 5.6 E-3 |
RWDD2A | RWD domain containing 2A | 6q14.2 | -0.80 | 8.7 E-4 |
HSF2 | Heat shock transcription factor 2 | 6q22.31 | -0.78 | 1.6 E-3 |
BLR1 | Burkitt lymphomas receptor 1, GTP binding protein (chemokine (CXC motif) receptor 5) | 11q23.3 | -0.69 | 7.4 E-3 |
MIZF | MBD2-interacting zinc finger | 11q23.3 | -0.69 | 5.9 E-3 |
KPNA5 | Karyopherin alpha 5 (importin alpha 6) | 6q22.2 | -0.66 | 8.7 E-3 |
LMO4 | LIM domain only 4 | 1p22.3 | -0.66 | 3.2 E-3 |
MUTYH | MutY homolog (E. coli) | 1p34.3-p32.1 | -0.65 | 4.9 E-4 |
REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 6q21 | -0.65 | 8.8 E-3 |
EPHB2 | Ephrin B2 | 1p36.1-p35 | -0.64 | 6.7 E-3 |
DGKZ | Diacylglycerol kinase, zeta 104kDa | 11p11.2 | -0.64 | 9.2 E-3 |
TSPYL4 | TSPY-like 4 | 6q22.1 | -0.63 | 1.6 E-3 |
DBT | Dihydrolipoamide branched chain transacylase E2 | 1p31 | -0.58 | 5.8 E-3 |
FOXO3 | Forkhead box O3 | 6q21 | -0.53 | 5.7 E-3 |
PPP2R1B | Protein phosphatase 2, regulatory subunit A, beta isoform | 11q23.2 | -0.51 | 2.7 E-3 |
PTPRK | Protein tyrosine phosphatase, receptor type, kappa | 6q22.2-q22.3 | -0.08 | 4.3 E-4 |