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Table 4 Details of genes located in regions of genomic difference with concordant differences in expression levels between AC and SCC

From: Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer

Symbol

Gene Name

Cytoband

Difference in expression (log2 SCC-AC)

P value

TP73L

Tumour protein 73-like

3q28

2.94

1.69 E-10

CSTA

Cystatin A (Stefin A)

3q21

2.27

3.42 E-8

ATP1B3

ATPase, Na+/K+ transporting, beta 3 polypeptide

3q23

1.46

1.06 E-6

VNN2

Vanin 2

6q23-q24

1.34

1.00 E-4

ABCC5

ATP-binding cassette, subfamily C, member 5

3q27

1.28

2.2 E-4

UPK1B

Uroplakin 1B

3q13.3-q21

1.12

3.3 E-3

RBP1

Retinol binding protein 1

3q23

1.12

1.98 E-3

SGK

Serum/glucocorticoid regulated kinase

6q23

1.06

1.3 E-4

TNFSF10/TRAIL

Tumour necrosis factor (ligand) superfamily, member 10/TNF-related apoptosis-inducing ligand

3q26

1.05

1.7 E-4

TNFAIP3

Tumour necrosis factor, alpha-induced protein 33

6q23

0.84

5.0 E-4

PFN2

Profilin 2

3q25.1-25.2

0.83

8.1 E-3

PLOD2

Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

3q23-q24

0.80

6.7 E-3

B3GNT5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

3q28

0.80

2.8 E-3

EIF4A2

Eukaryotic translation initiation factor 4A, isoform 2

3q28

0.66

4.1 E-3

MAP3K4

Mitogen activated protein kinase kinase kinase 4

6q26

0.59

1.8 E-3

PDCD10

Programmed cell death 10

3q26.1

0.58

2.9 E-3

SEP1

5'-3' exoribonuclease 1

3q25-q26.1

0.54

8.2 E-3

NCK1

NCK adaptor protein

3q21

0.52

7.3 E-3

GPR126

G-protein coupled receptor 126

6q24.1

0.52

1.7 E-3

LSAMP

Limbic system-associated membrane protein

3q13.2-q21

0.49

3.4 E-3

DZIP3

Zinc finger DAZ interacting protein

3q13.13

0.45

4.9 E-3

PIK3A2

Phosphoinositide-3-kinase, catalytic, alpha

3q26.3

0.44

9.2 E-3

WASF-1

WAS protein family, member 1

6q21-q22

0.44

8.3 E-3

CITED2/MRG1

CBP/P300-interacting transactivator, with GLU/ASP rich carboxy-terminal domain 2/Melanocyte specific gene 1 related gene 1

6q23.3

-0.63

8.0 E-3