Figure 4From: A human ribonuclease induces apoptosis associated with p21WAF1/CIP1induction and JNK inactivation Nuclear and cellular morphological effects of PE5 and onconase on the NCI/ADR-RES cell line. Overnight serum-starved NCI/ADR-RES cells were treated with 35 μM PE5 or 5 μM onconase for 72 h. Subsequently, Hoechst 33342 and calcein/PI staining were performed and observed under a confocal laser microscope. Bar 50 μm.Back to article page