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Figure 5 | BMC Cancer

Figure 5

From: Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma

Figure 5

Silencing of GPR39 expression suppresses tumorigenic ability of GPR39. (A) GPR39 expression was efficiently decreased by the treatment of siGPR39 by RT-PCR. Relative expression level was measured by densitometer and summarized in the right panel. **P < 0.01. (B) Growth curve of KYSE180 cells treated with GPR39 siRNA was compared with control siRNA treated cells by cell growth assay. **P < 0.01. (C) Cell migration assay was used to compare the frequency of migratory cells between KYSE180 cells treated with control siRNA and GPR39 siRNA. (D) DNA content between control siRNA and GPR39 siRNA treated cells were compared by Flow-cytometry. *P < 0.05.

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