Figure 2
From: Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells
Basal expression profile of colon cancer cell lines. Basal levels of (a), PXR exon 5-6; (b), PXR exon 1a-2; (c), CYP3A4; and (d), VDR transcripts in LS180, LoVo, Caco-2, HT29, HCT116 and SW48 cells. The vertical axis indicates a relative transcript level (ratio to LS180 cells). The transcripts indicated by * (PXR exon 5-6 transcript in SW48 cells and CYP3A4 transcript in HCT116 cells) were not detected and we estimated the minimum detectable levels among gradually diluted calibration samples (0.00257 and 0.0399, respectively).