Table 2 Representative percentages of HCT11 p53-/- cells in the different cell cycle phases following Nutlin-3 or Etoposide treatment as described in Additional file 2.
From: A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation
p53-/- | subG1 | G1 | S | G2/M |
|---|---|---|---|---|
Control | 3.2 | 56.3 | 14.8 | 25.7 |
Nut 10 nM | 5.7 | 19.5 | 25.3 | 49.5 |
Nut 15 nM | 7.7 | 18.6 | 22.7 | 51.0 |
Nut 20 nM | 7.2 | 18.3 | 22.7 | 51.8 |
Etoposide | 10.2 | 13.7 | 19.1 | 57.0 |