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Table 1 Regimens and drug doses of control and experimental arms

From: Effects on quality of life of weekly docetaxel-based chemotherapy in patients with locally advanced or metastatic breast cancer: results of a single-centre randomized phase 3 trial

Setting Treatment Arm Regimens Dose Schedule Reference
Locally advanced Control Epirubicin 75 mg/m², d 1 Every 3 weeks for 4 cycles de Matteis A, 2002
   Docetaxel 80 mg/m², d 1   
  Experimental Epirubicin 30 mg/m², dd 1-8-15 Every 4 weeks for 3 cycles Wenzel C, 2002
   Docetaxel 35 mg/m², dd 1-8-15   
Metastatic, no previous anthracyclines Control Epirubicin 60 mg/m², d 1 Every 3 weeks for 6 cycles Trudeau ME, 1999
   Docetaxel 75 mg/m², d 1   
  Experimental Epirubicin 25 mg/m², dd 1-8-15 Every 4 weeks for 6 cycles Wenzel C, 2002
   Docetaxel 30 mg/m², dd 1-8-15   
Metastatic, previously treated with anthracyclines Control Capecitabine 1000 mg/m², b.i.d., dd 1-14 Every 3 weeks for 6 cycles Pronk LC, 2000
   Docetaxel 75 mg/m², d 1   
  Experimental Capecitabine 625 mg/m², b.i.d., dd 5-18 Every 4 weeks for 6 cycles Nadella P, 2002
   Docetaxel 35 mg/m², dd 1-8-15