Figure 4

IR-, cisplatin-, etoposide-, and doxorubicin-mediated effect on cell cycle progression in DAOY MB cells. Cell cycle analysis following IR (A), exposure to cisplatin (B), etoposide (C), and doxorubicin (D). DAOY MB cells were irradiated with 5 Gy or treated with cisplatin (0.15 μg/ml), etoposide (0.19 μg/ml), or doxorubicin (0.02 μg/ml), and subjected to cell cycle determination by propidium iodide staining and FACS analysis at the time points indicated. The percentages of cells in G1, S, G2/M, and sub-G1 phases of the cell division cycle are indicated ± standard deviation (n = 2).