Table 2 Methylation Δbeta values (methylation frequencies) between the outcome groups DOD and NED.
From: Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma
Gene | CpG site | In CpG island | Mean DOD (SD) | Mean NED (SD) | Δbeta value |
|---|---|---|---|---|---|
SCNN1A | cg18738906 | yes | 0.88 (0.21) | 0.65 (0.27) | 0.23*** |
cg26215727 | no | 0.47 (0.20) | 0.31 (0.17) | 0.16*** | |
PRKCDBP | cg05628549 | yes | 0.53 (0.28) | 0.34 (0.26) | 0.18* |
cg16245261 | yes | 0.45 (0.34) | 0.20 (0.23) | 0.25** | |
cg18392783 | yes | 0.50 (0.32) | 0.26 (0.24) | 0.24** | |
cg18959478 | yes | 0.55 (0.31) | 0.32 (0.27) | 0.23** | |
KRT19 | cg11462865 | yes | 0.65 (0.24) | 0.43 (0.29) | 0.22** |
cg16585619 | no | 0.82 (0.09) | 0.81 (0.06) | 0.01 | |
TGFBI | cg00386408 | yes | 0.40 (0.24) | 0.32 (0.23) | 0.08 |
cg21034676 | yes | 0.28 (0.28) | 0.23 (0.24) | 0.04 | |
POU2F2 | cg21608489 | yes | 0.62 (0.22) | 0.59 (0.20) | 0.03 |
cg22054191 | yes | 0.22 (0.08) | 0.24 (0.10) | -0.02 | |
DUSP23 | cg10663017 | yes | 0.20 (0.25) | 0.11 (0.16) | 0.09 |
cg11104347 | yes | 0.17 (0.25) | 0.10 (0.15) | 0.08 | |
DHRS3 | cg01346152 | yes | 0.64 (0.30) | 0.64 (0.26) | 0.00 |
cg09229231 | yes | 0.03 (0.01) | 0.03 (0.01) | 0.00 | |
COL1A2 | cg18511007 | yes | 0.42 (0.27) | 0.35 (0.25) | 0.07 |
cg25300386 | yes | 0.37 (0.29) | 0.32 (0.27) | 0.05 |