The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

BMC Cancer

Table 1 Characteristics of cases and healthy individuals participating in this study

	Healthy individuals	Individuals with mild/moderate dysplasia	Individuals with severe dysplasia	Individuals with carcinomas
Total number of individuals in the study	(n = 18)	(n = 87)	(n = 13 )	(n = 121)
Number of men	6	61	7	66
Number of women	12	26	6	55
Mean age ± S.D.	56.8 ± 4.5	56.9 ± 3.6	54.9 ± 3.1	69.5 ± 12.0

Comparing the group of healthy individuals with the other groups showed that there were significantly more males in the group with mild dysplasia and CRC (p < 0.001; Chi Squared test). The mean age is significantly higher among patients with CRC compared to the three other groups (p < 0.001; Kruskal-Wallis and Dunn's Multiple Comparison test).

ISSN: 1471-2407