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Table 1 Summary of Pearson regression coefficients (R) and P values when comparing relative gene expression and relative FAZA retention in small tumor fragments obtained from 4 human FaDuddtumors and 4 murine SCCVII tumors.

From: In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors

FaDudd CA9 GLUT1 LDH GAPDH LOX ATF4
  R P R P R P R P R P R P
A 0.77 ≈10-4 0.85 3×10-6 0.72 < 10-3 0.17 0.48 0.77 < 10-3 -0.65 0.003
B 0.84 5×10-6 0.89 < 10-6 0.63 0.003 0.67 0.001 0.86 10-6 -0.73 < 10-3
C 0.48 0.04 0.51 0.02 0.62 0.004 0.33 0.17 0.73 < 10-3 -0.33 0.17
D 0.68 10-3 0.75 ≈10-3 0.73 < 10-3 -0.1 0.69 0.75 < 10-3 -0.54 0.02
Mean 0.69   0.75   0.67   0.18   0.78   -0.56  
Pooled 0.58 < 10-7 0.74 < 10-14 0.52 < 10-6 0.13 0.24 0.76 < 10-15 -0.45 < 10-4
SCCVII CA9 GLUT1 LDH GAPDH LOX ATF4
  R P R P R P R P R P R P
A 0.92 < 10-4 0.94 < 10-4 0.82 0.002 0.89 < 10-3 -0.54 0.08 0.70 0.02
B 0.89 < 10-6 0.76 < 10-3 0.50 0.03 0.80 < 10-4 -0.48 0.03 0.49 0.04
C 0.60 0.005 0.60 0.005 0.43 0.06 0.53 0.02 -0.35 0.13 0.08 0.7
D 0.70 < 10-3 0.47 0.03 -0.10 0.67 0.16 0.51 -0.30 0.20 0.36 0.1
Mean 0.78   0.69   0.41   0.59   -0.42   0.41  
Pooled 0.65 < 10-9 0.64 < 10-8 0.24 0.04 0.56 < 10-6 -0.38 0.001 0.39 < 10-3
  1. Analysis was performed on a per-tumor basis (A, B, C and D). Similar data analysis was also performed after data were pooled, i.e., for each gene the relative gene expression for all fragments for a given tumor type was plotted as function of relative FAZA content followed by regression analysis.