Table 3 Clinical characteristics of profiled GBC
From: Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma
Mutation | Gender | Smoking | Age | T | N | M | Stage | Histology | Differentiation |
|---|---|---|---|---|---|---|---|---|---|
PIK3CA E545K | F | yes | 75 | 1 | 2 | 0 | 1 | adenocarcinoma | Moderate |
PIK3CA E542K | F | no | 83 | 2 | 2 | 0 | 1 | adenocarcinoma | Poor |
PIK3CA E542K | M | yes | 82 | 3 | 1 | 0 | 2 | adenocarcinoma | Moderate |
PIK3CA E545K | F | unknown | 53 | 3 | 0 | 0 | 2 | adenosquamous carcinoma | Poor |
NRAS G12D | F | no | 56 | 2 | 1 | 1 | 4 | adenocarcinoma | Poor |
NRAS G12D | F | yes | 76 | 2 | 0 | 1 | 4 | adenocarcinoma | Moderate |
| Â | F | no | 68 | 3 | 2 | 0 | 2 | adenosquamous carcinoma | Poor |
| Â | F | no | 62 | 1 | 2 | 0 | 1 | adenocarcinoma | Moderate |
| Â | F | no | 62 | 3 | 1 | 0 | 2 | adenosquamous carcinoma | Poor |
| Â | F | unknown | 79 | 4 | 2 | 0 | 3 | adenocarcinoma | Moderate |
| Â | F | yes | 72 | 3 | 2 | 0 | 2 | adenocarcinoma | Unknown |
| Â | F | no | 57 | 3 | 2 | 0 | 2 | adenocarcinoma | Poor |
| Â | M | yes | 55 | 2 | 1 | 0 | 2 | adenocarcinoma | Poor |
| Â | F | no | 87 | 3 | 1 | 0 | 2 | adenocarcinoma | Moderate |
| Â | F | no | 63 | 1 | 0 | 0 | 1 | adenocarcinoma | Moderate |
| Â | M | unknown | 54 | 3 | 2 | 0 | 2 | adenocarcinoma | Poor |
| Â | M | no | 48 | 3 | 0 | 0 | 2 | adenocarcinoma | Poor |
| Â | F | yes | 52 | 3 | 2 | 1 | 4 | adenocarcinoma | Poor |
| Â | F | no | 60 | 3 | 0 | 1 | 4 | adenocarcinoma | Poor |
| Â | F | yes | 76 | 2 | 2 | 0 | 1 | adenocarcinoma | Poor |
| Â | F | yes | 75 | 1 | 2 | 0 | 1 | adenocarcinoma | Moderate |
| Â | F | no | 66 | 4 | 2 | 0 | 3 | Undifferentiated carcinoma | Poor |
| Â | F | yes | 57 | 4 | 2 | 1 | 4 | adenocarcinoma | Unknown |
| Â | F | no | 72 | 2 | 0 | 0 | 1 | adenocarcinoma | Moderate |
| Â | M | yes | 81 | 3 | 0 | 1 | 4 | adenocarcinoma | Poor |
| Â | F | no | 41 | 2 | 0 | 0 | 1 | adenocarcinoma | Unknown |
| Â | M | no | 68 | 2 | 0 | 0 | 1 | adenocarcinoma | Poor |
| Â | M | yes | 75 | 3 | 0 | 0 | 2 | adenosquamous carcinoma | Moderate |
| Â | F | yes | 70 | 2 | 2 | 0 | 1 | adenocarcinoma | Poor |
| Â | F | no | 74 | 3 | 2 | 0 | 2 | adenocarcinoma | Moderate |
| Â | M | no | 63 | 3 | 2 | 0 | 2 | adenocarcinoma | Poor |
| Â | F | yes | 58 | 2 | 0 | 0 | 1 | adenocarcinoma | Poor |
| Â | F | no | 67 | 3 | 0 | 1 | 4 | adenocarcinoma | Unknown |