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Table 3 Chemotherapy characteristics and on-treatment toxicities

From: Concurrent cisplatin, continuous infusion fluorouracil and radiotherapy followed by tailored consolidation treatment in non metastatic anal squamous cell carcinoma

Variables Number
Total number of cycles 98
Fluorouracil 97^
Cisplatin 94*
   Patients receiving  
2 cycles 5 (17.2%)
3 cycles 12 (41.4%)
4 cycles 12 (41.4%)
Cisplatin modification (total # of cycles = 94)  
   Full dose-intensity 70 (74.5%)
   Delay/modification 24
Cisplatin and/or Fluorouracil modification (total # of cycles over the first 2 cycles = 58)  
   Full dose-intensity 49 (70.7%)
   Delay/modification 9
   Reasons  
Haematological toxicities 2
Neutropenia (G3) 1
Leucopoenia (G1) 1
Non Haematological toxicities 5
Diarrhoea (G2) 1
Nausea (G2 and G3) 2
Nausea and Diarrhoea (G2) 1
Mucositis (G2) 1
Haematological and non-haematological toxicities 1
Diarrhoea (G2) and Leucopoenia (G2) 1
Other toxicities 1
Hypoacusia (G2) 1
  1. ^ 1 patient received C only
  2. * 5 patients received Fluorouracil only