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Table 4 Antibody seropositivity rates and mean serum antibody levels

From: Serum antibodies against genitourinary infectious agents in prostate cancer and benign prostate hyperplasia patients: a case-control study

 

Seroprevalence rate

Mean serum levels OD/CO

 

PCa

BPH

OR

95% CI

PCa

BPH

p

HPV 6

77 (24.1%)

21 (20.8%)

1.21

0.71-2.12

2.608

3.162

0.0964

HPV 11

40 (12.5%)

15 (14.9%)

0.82

0.44-1.60

2.554

2.259

0.9698

HPV 16

16 (5.0%)

10 (9.9%)

0.48

0.21-1.13

3.470

3.251

0.8743

HPV 18

8 (2.5%)

10 (9.9%)

0.23

0.09-0.61

1.496

1.365

0.9290

HPV 31

19 (5.9%)

8 (7.9%)

0.73

0.32-1.83

2.616

3.640

0.1053

HPV 33

7 (2.2%)

5 (5.0%)

0.43

0.13-1.48

2.156

3.620

0.3434

CMV

264 (80.2%)

91 (86.7%)

0.62

0.32-1.14

3.839

4.407

0.0004

HSV 1

313 (95.1%)

99 (94.3%)

1.19

0.42-2.97

3.760

3.832

0.9649

HSV 2

42 (12.8%)

14 (13.3%)

0.95

0.51-1.88

5.362

4.859

0.8056

Chlamydia trachomatis

18 (5.5%)

12 (11.4%)

0.45

0.21-0.99

1.281

1.210

0.6560

Mycoplasma hominis

60 (18.2%)

15 (14.3%)

1.34

0.74-2.55

NA

NA

-

Ureaplasma urealyticum

64 (19.5%)

11 (10.5%)

2.06

1.08-4.28

NA

NA

-

Neisseria gonorrhoeae

20 (6.1%)

6 (5.7%)

1.07

0.44-2.99

NA

NA

-

Treponema pallidum

1 (0.3%)

0 (0%)

NA

NA

NA

NA

-

  1. Antibody seropositivity rates for different genitourinary pathogens in cases and controls. Only reactive serum samples (OD/CO > 1.0) were considered for the calculation of mean serum antibody levels. PCa prostate cancer, BPH benign prostate hyperplasia, OR odds ratio, CI confidence interval, OD/CO optical density/cut-off, HPV human papillomavirus, CMV human cytomegalovirus, HSV herpes simplex virus, NA not applicable