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Table 2 Immunohistochemical staining of SAV1 and YAP1 protein in ccRCC

From: Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinoma

  

SAV1 immunoreactivity

  

positive

weak or negative

Total

YAP1

Cytoplasmic pattern*

28

9

37

 

Nuclear pattern**

7

31

38

 

total

35

40

75

  

Fisher's exact test

p < 0.001

  1. *Cytoplasmic pattern; YAP1 is mainly localized in cytoplasm of tumor
  2. **Nuclear pattern; YAP1 is mainly localized in nucleus of tumor cells