From: Improved blood tests for cancer screening: general or specific?
Stage | Stage description |
---|---|
Stage 1 | Development of test using clinical samples |
Stage 2 | Early clinical testing of efficacy (sensitivity, specificity, NPV, PPV, AUROC) |
Stage 3 | Validation (larger numbers, defined by confidence intervals on AUROC) |
Stage 4 | Implementation and impact (trials or modelling to answer effectiveness questions) |