Table 3 Univariate and multivariate analysis of predictors of survival after bone metastases in 30 HCC patients undergoing LT

Pre-LT

Gender

Female

4

50.0

0

2.7

0.241

0.428

Male

26

42.3

29.0

8.6

Age (years)

≤50

17

28.2

21.2

8.6

0.697

0.180

>50

13

46.2

19.2

15.1

HbsAg

-

3

0

0

5.0

0.190

0.201

+

27

44.1

27.1

9.8

Γ-GT

≤75

14

42.9

21.4

11.2

0.814

0.099

>75

16

30.0

20.0

6.3

AFP

≤400

16

37.5

23.4

8.6

0.738

0.557

>400

14

34.3

17.1

6.3

Child-Pugh Classification

A

22

26.5

21.2

6.3

0.240

0.099

B

8

62.5

33.3

16.6

Shanghai criteria

Exceeding

14

34.3

12.9

8.6

0.962

0.570

Within

16

37.5

18.8

7.9

UCSF

Exceeding

18

38.1

8.5

8.6

0.597

0.972

Within

12

33.3

33.3

6.3

Milan

Exceeding

20

50

20

11.2

0.939

0.364

Within

10

20

20

4.1

Interval between diagnosis of HCC and LT

≤0.5 year

17

35.3

22.1

8.6

0.947

0.976

>0.5 year

13

36.9

18.5

9.8

Post-LT

KPS

≥80

14

56.3

30.1

15.6

0.032

0.003

<80

16

18.8

12.5

4.1

Γ-GT

≤75

11

53.0

31.8

23.9

0.116

0.385

>75

19

26.3

14.0

6.3

AFP

≤400

15

40.0

25.0

11.2

0.531

0.926

>400

15

32.0

16.0

5.0

Child-Pugh Classification

A

23

43.0

27.3

11.2

0.209

0.294

B

7

14.3

0

6.3

Soft-tissue extension

Absent

23

29.8

19.9

7.9

0.470

0.974

Present

7

57.1

19.0

23.9

No. of bone metastases

Solitary

14

50.0

25.7

15.6

0.245

0.456

≥2 sites

16

23.4

15.6

7.9

Intrahepatic tumor control

uncontrolled

10

20.0

10.0

3.0

0.003

0.008

Well-controlled

20

55.0

31.4

15.1

Concurrent metastases

Absent

15

38.9

15.6

4.1

0.565

0.170

Present

15

40.0

24.0

9.8