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Figure 4 | BMC Cancer

Figure 4

From: Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

Figure 4

Twist activates β-catenin pathway. (a) The expression of total, membrane, cytosol, nuclear and phosphorylated forms of β-catenin were examined by Western blotting. β-tubulin served as a loading control. (b) The activation of β-catenin was examined by measuring the transcription activity of Top/Fop luciferase in Hela and MCF cells and their corresponding stable transfectants (mean ± SD of three separate experiments). * and # P < 0.05 for Hela and MCF7 cells compared with their corresponding Twist-overexpressing cells.

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