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Table 1 Univariate analysis of clinical factors and GPS for progression free survival (n = 402)

From: Prognostic significance of a systemic inflammatory response in patients receiving first-line palliative chemotherapy for recurred or metastatic gastric cancer

 

Patients (%)

mPFS months (95% CI)

P-value

Age

<60

203 (50.5)

4.3 (3.8-4.7)

0.840

≥ 60

199 (49.5)

4.5 (3.9-5.1)

 

Gender

Male

293 (72.9)

4.5 (3.9-5.0)

0.381

Female

109 (27.1)

4.3 (3.6-4.9)

 

Liver Mets

Yes

125 (31.1)

4.1 (3.6-4.5)

0.243

No

277 (68.9)

4.6 (3.9-5.2)

 

Peritoneal Mets

Yes

159 (39.6)

4.3 (3.8-4.8)

0.128

No

243 (60.4)

4.6 (3.9-5.2)

 

Bone Mets

Yes

28 (7.0)

3.9 (2.4-5.3)

0.032

No

374 (93.0)

4.5 (4.0-5.0)

 

Albumin

<3.5

77 (19.2)

3.4 (2.2-4.5)

0.013

≥ 3.5

325 (80.8)

4.6 (4.1-5.2)

 

CRP

≤ 1

262 (65.1)

5.3 (4.5-6.0)

0.001

>1

140 (34.9)

3.4 (2.7-4.1)

 

ECOG PS

0-1

329 (81.8)

4.6 (4.0-5.1)

0.002

≥ 2

73 (48.2)

3.0 (2.0-3.9)

 

GPS

0

238 (59.2)

5.5 (4.8-6.2)

0.001

1

111 (27.6)

3.4 (2.7-4.1)

 

2

53 (13.2)

3.3 (2.0-4.7)

 
  1. mPFS: median progression free survival, Mets: Metastasis, CRP: C-reactive protein, ECOG PS: Eastern Cooperative Oncology Group, performance status, GPS: Glascow prognostic score