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Table 4 Pathological complete response relative to molecular subtypes of tumor

From: Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

 

Tumor classification (+: yes/-: no)

Tumor response

 
 

ER/PR

HER2

Ki67

Neoadjuvant

All

pCR no

pCR yes

 
    

trastuzumab

N

%

n

%

n

%

P

Hormone receptor-positive

+

-

+

NA

176

100

162

92.0

14

8.0

0.05

 

+

-

-

NA

140

100

136

97.1

4

2.9

 
 

+ or -

+

+

+ or -

88

100

49

55.7

39

44.3

0.03

 

+ or -

+

-

+ or -

14

100

12

85.7

2

14.3

 

HER2-positive

+ or -

+

+ or -

+

50

100

24

48.0

26

52.0

0.03

 

+ or -

+

+ or -

-

52

100

37

71.2

15

28.8

 

Triple negative

-

-

+

NA

122

100

62

50.8

60

49.2

0.12

 

-

-

-

NA

7

100

6

85.7

1

14.3

 

All

+ or -

+ or -

+ or -

+ or -

547

100

427

78.1

120

21.9

 
  1. ER, estrogen receptor; HER2, HER2/neu receptor; NA, not applicable; PR, progesterone receptor.