TY - JOUR AU - Jemal, A. AU - Bray, F. AU - Center, M. M. AU - Ferlay, J. AU - Ward, E. AU - Forman, D. PY - 2011 DA - 2011// TI - Global cancer statistics JO - CA Cancer J Clin VL - 61 UR - https://doi.org/10.3322/caac.20107 DO - 10.3322/caac.20107 ID - Jemal2011 ER - TY - JOUR AU - Boulet, G. A. AU - Horvath, C. A. AU - Berghmans, S. AU - Bogers, J. PY - 2008 DA - 2008// TI - Human papillomavirus in cervical cancer screening: important role as biomarker JO - Cancer Epidemiol Biomarkers Prev VL - 17 UR - https://doi.org/10.1158/1055-9965.EPI-07-2865 DO - 10.1158/1055-9965.EPI-07-2865 ID - Boulet2008 ER - TY - JOUR AU - Franco, E. L. AU - Duarte-Franco, E. AU - Ferenczy, A. PY - 2001 DA - 2001// TI - Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection JO - CMAJ VL - 164 ID - Franco2001 ER - TY - JOUR AU - Hannun, Y. A. PY - 1997 DA - 1997// TI - Apoptosis and the dilemma of cancer chemotherapy JO - Blood VL - 89 ID - Hannun1997 ER - TY - JOUR AU - Elmore, S. PY - 2007 DA - 2007// TI - Apoptosis: a review of programmed cell death JO - Toxicol Pathol VL - 35 UR - https://doi.org/10.1080/01926230701320337 DO - 10.1080/01926230701320337 ID - Elmore2007 ER - TY - JOUR AU - Herr, I. AU - Debatin, K. M. PY - 2001 DA - 2001// TI - Cellular stress response and apoptosis in cancer therapy JO - Blood VL - 98 UR - https://doi.org/10.1182/blood.V98.9.2603 DO - 10.1182/blood.V98.9.2603 ID - Herr2001 ER - TY - JOUR AU - Ewald, J. A. AU - Desotelle, J. A. AU - Wilding, G. AU - Jarrard, D. F. PY - 2010 DA - 2010// TI - Therapy-induced senescence in cancer JO - J Natl Cancer Inst VL - 102 UR - https://doi.org/10.1093/jnci/djq364 DO - 10.1093/jnci/djq364 ID - Ewald2010 ER - TY - JOUR AU - Roninson, I. B. PY - 2003 DA - 2003// TI - Tumor cell senescence in cancer treatment JO - Cancer Res VL - 63 ID - Roninson2003 ER - TY - JOUR AU - Campisi, J. PY - 2011 DA - 2011// TI - Cellular senescence: putting the paradoxes in perspective JO - Curr Opin Genet Dev VL - 21 UR - https://doi.org/10.1016/j.gde.2010.10.005 DO - 10.1016/j.gde.2010.10.005 ID - Campisi2011 ER - TY - JOUR AU - Gonzalez, V. M. AU - Fuertes, M. A. AU - Alonso, C. AU - Perez, J. M. PY - 2001 DA - 2001// TI - Is cisplatin-induced cell death always produced by apoptosis? JO - Mol Pharmacol VL - 59 ID - Gonzalez2001 ER - TY - JOUR AU - Losa, J. H. AU - Parada Cobo, C. AU - Viniegra, J. G. AU - Sanchez-Arevalo Lobo, V. J. AU - Ramon y Cajal, S. AU - Sanchez-Prieto, R. PY - 2003 DA - 2003// TI - Role of the p38 MAPK pathway in cisplatin-based therapy JO - Oncogene VL - 22 UR - https://doi.org/10.1038/sj.onc.1206608 DO - 10.1038/sj.onc.1206608 ID - Losa2003 ER - TY - JOUR AU - Lerma-Diaz, J. M. AU - Hernandez-Flores, G. AU - Dominguez-Rodriguez, J. R. AU - Ortiz-Lazareno, P. C. AU - Gomez-Contreras, P. AU - Cervantes-Munguia, R. AU - Scott-Algara, D. AU - Aguilar-Lemarroy, A. AU - Jave-Suarez, L. F. AU - Bravo-Cuellar, A. PY - 2006 DA - 2006// TI - In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation JO - Immunol Lett VL - 103 UR - https://doi.org/10.1016/j.imlet.2005.10.019 DO - 10.1016/j.imlet.2005.10.019 ID - Lerma-Diaz2006 ER - TY - JOUR AU - Gomez-Contreras, P. C. AU - Hernandez-Flores, G. AU - Ortiz-Lazareno, P. C. AU - Del Toro-Arreola, S. AU - Delgado-Rizo, V. AU - Lerma-Diaz, J. M. AU - Barba-Barajas, M. AU - Dominguez-Rodriguez, J. R. AU - Bravo Cuellar, A. PY - 2006 DA - 2006// TI - In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: increased BCL-2 and BAX protein expression JO - Chemotherapy VL - 52 UR - https://doi.org/10.1159/000096003 DO - 10.1159/000096003 ID - Gomez-Contreras2006 ER - TY - JOUR AU - Hernandez-Flores, G. AU - Bravo-Cuellar, A. AU - Aguilar-Luna, J. C. AU - Lerma-Diaz, J. M. AU - Barba-Barajas, M. AU - Orbach-Arbouys, S. PY - 2010 DA - 2010// TI - [In vitro induction of apoptosis in acute myelogenous and lymphoblastic leukemia cells by adriamycine is increased by pentoxifylline] JO - Presse Med VL - 39 UR - https://doi.org/10.1016/j.lpm.2010.07.013 DO - 10.1016/j.lpm.2010.07.013 ID - Hernandez-Flores2010 ER - TY - JOUR AU - Bravo-Cuellar, A. AU - Ortiz-Lazareno, P. C. AU - Lerma-Diaz, J. M. AU - Dominguez-Rodriguez, J. R. AU - Jave-Suarez, L. F. AU - Aguilar-Lemarroy, A. AU - del Toro-Arreola, S. AU - de Celis-Carrillo, R. AU - Sahagun-Flores, J. E. AU - de Alba-Garcia, J. E. PY - 2010 DA - 2010// TI - Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence JO - Mol Cancer VL - 9 UR - https://doi.org/10.1186/1476-4598-9-114 DO - 10.1186/1476-4598-9-114 ID - Bravo-Cuellar2010 ER - TY - JOUR AU - Franken, N. A. AU - Rodermond, H. M. AU - Stap, J. AU - Haveman, J. AU - van Bree, C. PY - 2006 DA - 2006// TI - Clonogenic assay of cells in vitro JO - Nat Protoc VL - 1 UR - https://doi.org/10.1038/nprot.2006.339 DO - 10.1038/nprot.2006.339 ID - Franken2006 ER - TY - JOUR AU - Chou, T. C. PY - 2010 DA - 2010// TI - Drug combination studies and their synergy quantification using the Chou-Talalay method JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-09-1947 DO - 10.1158/0008-5472.CAN-09-1947 ID - Chou2010 ER - TY - JOUR AU - Chou, T. C. AU - Motzer, R. J. AU - Tong, Y. AU - Bosl, G. J. PY - 1994 DA - 1994// TI - Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design JO - J Natl Cancer Inst VL - 86 UR - https://doi.org/10.1093/jnci/86.20.1517 DO - 10.1093/jnci/86.20.1517 ID - Chou1994 ER - TY - JOUR AU - Chou, T. C. PY - 2006 DA - 2006// TI - Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies JO - Pharmacol Rev VL - 58 UR - https://doi.org/10.1124/pr.58.3.10 DO - 10.1124/pr.58.3.10 ID - Chou2006 ER - TY - JOUR AU - Reynolds, C. P. AU - Maurer, B. J. PY - 2005 DA - 2005// TI - Evaluating response to antineoplastic drug combinations in tissue culture models JO - Methods Mol Med VL - 110 ID - Reynolds2005 ER - TY - CHAP AU - Martin, D. AU - Lenardo, M. PY - 2001 DA - 2001// TI - Morphological, biochemical, and flow cytometric assays of apoptosis BT - Curr Protoc Mol Biol ID - Martin2001 ER - TY - JOUR AU - Geske, F. J. AU - Lieberman, R. AU - Strange, R. AU - Gerschenson, L. E. PY - 2001 DA - 2001// TI - Early stages of p53-induced apoptosis are reversible JO - Cell Death Differ VL - 8 UR - https://doi.org/10.1038/sj.cdd.4400786 DO - 10.1038/sj.cdd.4400786 ID - Geske2001 ER - TY - JOUR AU - Bohm, L. AU - Roos, W. P. AU - Serafin, A. M. PY - 2003 DA - 2003// TI - Inhibition of DNA repair by Pentoxifylline and related methylxanthine derivatives JO - Toxicology VL - 193 UR - https://doi.org/10.1016/S0300-483X(03)00294-4 DO - 10.1016/S0300-483X(03)00294-4 ID - Bohm2003 ER - TY - JOUR AU - Reddel, R. R. PY - 2000 DA - 2000// TI - The role of senescence and immortalization in carcinogenesis JO - Carcinogenesis VL - 21 UR - https://doi.org/10.1093/carcin/21.3.477 DO - 10.1093/carcin/21.3.477 ID - Reddel2000 ER - TY - JOUR AU - Schmitt, C. A. PY - 2007 DA - 2007// TI - Cellular senescence and cancer treatment JO - Biochim Biophys Acta VL - 1775 ID - Schmitt2007 ER - TY - JOUR AU - Campisi, J. AU - Kim, S. H. AU - Lim, C. S. AU - Rubio, M. PY - 2001 DA - 2001// TI - Cellular senescence, cancer and aging: the telomere connection JO - Exp Gerontol VL - 36 UR - https://doi.org/10.1016/S0531-5565(01)00160-7 DO - 10.1016/S0531-5565(01)00160-7 ID - Campisi2001 ER - TY - JOUR AU - Theron, T. AU - Bohm, L. PY - 2000 DA - 2000// TI - Influence of the G2 cell cycle block abrogator pentoxifylline on the expression and subcellular location of cyclin B1 and p34cdc2 in HeLa cervical carcinoma cells JO - Cell Prolif VL - 33 UR - https://doi.org/10.1046/j.1365-2184.2000.00160.x DO - 10.1046/j.1365-2184.2000.00160.x ID - Theron2000 ER - TY - JOUR AU - Theron, T. AU - Binder, A. AU - Verheye-Dua, F. AU - Bohm, L. PY - 2000 DA - 2000// TI - The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifylline JO - Int J Radiat Biol VL - 76 UR - https://doi.org/10.1080/09553000050134438 DO - 10.1080/09553000050134438 ID - Theron2000 ER - TY - JOUR AU - Serafin, A. M. AU - Binder, A. B. AU - Bohm, L. PY - 2001 DA - 2001// TI - Chemosensitivity of prostatic tumour cell lines under conditions of G2 block abrogation JO - Urol Res VL - 29 UR - https://doi.org/10.1007/s002400100186 DO - 10.1007/s002400100186 ID - Serafin2001 ER - TY - JOUR AU - Rishi, L. AU - Gahlot, S. AU - Kathania, M. AU - Majumdar, S. PY - 2009 DA - 2009// TI - Pentoxifylline induces apoptosis in vitro in cutaneous T cell lymphoma (HuT-78) and enhances FasL mediated killing by upregulating Fas expression JO - Biochem Pharmacol VL - 77 UR - https://doi.org/10.1016/j.bcp.2008.09.018 DO - 10.1016/j.bcp.2008.09.018 ID - Rishi2009 ER - TY - JOUR AU - Henkels, K. M. AU - Turchi, J. J. PY - 1999 DA - 1999// TI - Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines JO - Cancer Res VL - 59 ID - Henkels1999 ER - TY - JOUR AU - Horvath, B. AU - Vekasi, J. AU - Kesmarky, G. AU - Toth, K. PY - 2008 DA - 2008// TI - In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model JO - Clin Hemorheol Microcirc VL - 40 ID - Horvath2008 ER - TY - JOUR AU - Bragado, P. AU - Armesilla, A. AU - Silva, A. AU - Porras, A. PY - 2007 DA - 2007// TI - Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation JO - Apoptosis VL - 12 UR - https://doi.org/10.1007/s10495-007-0082-8 DO - 10.1007/s10495-007-0082-8 ID - Bragado2007 ER - TY - JOUR AU - Weir, N. M. AU - Selvendiran, K. AU - Kutala, V. K. AU - Tong, L. AU - Vishwanath, S. AU - Rajaram, M. AU - Tridandapani, S. AU - Anant, S. AU - Kuppusamy, P. PY - 2007 DA - 2007// TI - Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK JO - Cancer Biol Ther VL - 6 UR - https://doi.org/10.4161/cbt.6.2.3577 DO - 10.4161/cbt.6.2.3577 ID - Weir2007 ER - TY - JOUR AU - Yeh, P. Y. AU - Yeh, K. H. AU - Chuang, S. E. AU - Song, Y. C. AU - Cheng, A. L. PY - 2004 DA - 2004// TI - Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M402362200 DO - 10.1074/jbc.M402362200 ID - Yeh2004 ER - TY - JOUR AU - Zhang, Y. AU - Qu, X. AU - Jing, W. AU - Hu, X. AU - Yang, X. AU - Hou, K. AU - Teng, Y. AU - Zhang, J. AU - Liu, Y. PY - 2009 DA - 2009// TI - GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling JO - Anticancer Drugs VL - 20 UR - https://doi.org/10.1097/CAD.0b013e328322fbaa DO - 10.1097/CAD.0b013e328322fbaa ID - Zhang2009 ER - TY - JOUR AU - Amran, D. AU - Sancho, P. AU - Fernandez, C. AU - Esteban, D. AU - Ramos, A. M. AU - de Blas, E. AU - Gomez, M. AU - Palacios, M. A. AU - Aller, P. PY - 2005 DA - 2005// TI - Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction in intracellular drug accumulation JO - Biochim Biophys Acta VL - 1743 UR - https://doi.org/10.1016/j.bbamcr.2004.10.009 DO - 10.1016/j.bbamcr.2004.10.009 ID - Amran2005 ER - TY - JOUR AU - Deng, Q. AU - Liao, R. AU - Wu, B. L. AU - Sun, P. PY - 2004 DA - 2004// TI - High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M308644200 DO - 10.1074/jbc.M308644200 ID - Deng2004 ER - TY - JOUR AU - Zubova, S. G. AU - Bykova, T. V. AU - Zubova Iu, G. AU - Romanov, V. S. AU - Aksenov, N. D. AU - Pospelov, V. A. AU - Pospelova, T. V. PY - 2007 DA - 2007// TI - [Role of p38alpha kinase in activation of premature senescence program in transformed mouse fibroblasts] JO - Tsitologiia VL - 49 ID - Zubova2007 ER - TY - JOUR AU - Kwong, J. AU - Hong, L. AU - Liao, R. AU - Deng, Q. AU - Han, J. AU - Sun, P. PY - 2009 DA - 2009// TI - p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M808327200 DO - 10.1074/jbc.M808327200 ID - Kwong2009 ER - TY - JOUR AU - Sethi, G. AU - Sung, B. AU - Aggarwal, B. B. PY - 2008 DA - 2008// TI - Nuclear factor-kappaB activation: from bench to bedside JO - Exp Biol Med (Maywood) VL - 233 UR - https://doi.org/10.3181/0707-MR-196 DO - 10.3181/0707-MR-196 ID - Sethi2008 ER - TY - JOUR AU - Fiebig, A. A. AU - Zhu, W. AU - Hollerbach, C. AU - Leber, B. AU - Andrews, D. W. PY - 2006 DA - 2006// TI - Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line JO - BMC Cancer VL - 6 UR - https://doi.org/10.1186/1471-2407-6-213 DO - 10.1186/1471-2407-6-213 ID - Fiebig2006 ER - TY - JOUR AU - Suen, D. F. AU - Norris, K. L. AU - Youle, R. J. PY - 2008 DA - 2008// TI - Mitochondrial dynamics and apoptosis JO - Genes Dev VL - 22 UR - https://doi.org/10.1101/gad.1658508 DO - 10.1101/gad.1658508 ID - Suen2008 ER - TY - JOUR AU - Chandele, A. AU - Prasad, V. AU - Jagtap, J. C. AU - Shukla, R. AU - Shastry, P. R. PY - 2004 DA - 2004// TI - Upregulation of survivin in G2/M cells and inhibition of caspase 9 activity enhances resistance in staurosporine-induced apoptosis JO - Neoplasia VL - 6 UR - https://doi.org/10.1016/S1476-5586(04)80051-4 DO - 10.1016/S1476-5586(04)80051-4 ID - Chandele2004 ER - TY - JOUR AU - Gazzaniga, P. AU - Gradilone, A. AU - Petracca, A. AU - Nicolazzo, C. AU - Raimondi, C. AU - Iacovelli, R. AU - Naso, G. AU - Cortesi, E. PY - 2010 DA - 2010// TI - Molecular markers in circulating tumour cells from metastatic colorectal cancer patients JO - J Cell Mol Med VL - 14 UR - https://doi.org/10.1111/j.1582-4934.2010.01117.x DO - 10.1111/j.1582-4934.2010.01117.x ID - Gazzaniga2010 ER - TY - JOUR AU - Srivastava, R. K. AU - Sasaki, C. Y. AU - Hardwick, J. M. AU - Longo, D. L. PY - 1999 DA - 1999// TI - Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription JO - J Exp Med VL - 190 UR - https://doi.org/10.1084/jem.190.2.253 DO - 10.1084/jem.190.2.253 ID - Srivastava1999 ER - TY - JOUR AU - Shah, M. A. AU - Schwartz, G. K. PY - 2001 DA - 2001// TI - Cell cycle-mediated drug resistance: an emerging concept in cancer therapy JO - Clin Cancer Res VL - 7 ID - Shah2001 ER - TY - JOUR AU - Yoon, S. S. AU - Ahn, K. S. AU - Kim, S. H. AU - Shim, Y. M. AU - Kim, J. PY - 2001 DA - 2001// TI - In vitro establishment of cis-diammine-dichloroplatinum(II) resistant lung cancer cell line and modulation of apoptotic gene expression as a mechanism of resistant phenotype JO - Lung Cancer VL - 33 UR - https://doi.org/10.1016/S0169-5002(01)00205-7 DO - 10.1016/S0169-5002(01)00205-7 ID - Yoon2001 ER - TY - JOUR AU - Weller, M. PY - 1998 DA - 1998// TI - Predicting response to cancer chemotherapy: the role of p53 JO - Cell Tissue Res VL - 292 UR - https://doi.org/10.1007/s004410051072 DO - 10.1007/s004410051072 ID - Weller1998 ER - TY - JOUR AU - Fricker, M. AU - Papadia, S. AU - Hardingham, G. E. AU - Tolkovsky, A. M. PY - 2010 DA - 2010// TI - Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons JO - J Neurochem VL - 114 UR - https://doi.org/10.1111/j.1471-4159.2010.06804.x DO - 10.1111/j.1471-4159.2010.06804.x ID - Fricker2010 ER - TY - JOUR AU - Qin, J. Z. AU - Stennett, L. AU - Bacon, P. AU - Bodner, B. AU - Hendrix, M. J. AU - Seftor, R. E. AU - Seftor, E. A. AU - Margaryan, N. V. AU - Pollock, P. M. AU - Curtis, A. PY - 2004 DA - 2004// TI - p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas JO - Mol Cancer Ther VL - 3 ID - Qin2004 ER - TY - JOUR AU - Perez-Galan, P. AU - Roue, G. AU - Villamor, N. AU - Montserrat, E. AU - Campo, E. AU - Colomer, D. PY - 2006 DA - 2006// TI - The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status JO - Blood VL - 107 UR - https://doi.org/10.1182/blood-2005-05-2091 DO - 10.1182/blood-2005-05-2091 ID - Perez-Galan2006 ER - TY - JOUR AU - Sankala, H. M. AU - Hait, N. C. AU - Paugh, S. W. AU - Shida, D. AU - Lepine, S. AU - Elmore, L. W. AU - Dent, P. AU - Milstien, S. AU - Spiegel, S. PY - 2007 DA - 2007// TI - Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-07-2090 DO - 10.1158/0008-5472.CAN-07-2090 ID - Sankala2007 ER - TY - JOUR AU - Rodier, F. AU - Campisi, J. PY - 2011 DA - 2011// TI - Four faces of cellular senescence JO - J Cell Biol VL - 192 UR - https://doi.org/10.1083/jcb.201009094 DO - 10.1083/jcb.201009094 ID - Rodier2011 ER - TY - JOUR AU - Linskens, M. H. AU - Harley, C. B. AU - West, M. D. AU - Campisi, J. AU - Hayflick, L. PY - 1995 DA - 1995// TI - Replicative senescence and cell death JO - Science VL - 267 UR - https://doi.org/10.1126/science.7848496 DO - 10.1126/science.7848496 ID - Linskens1995 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/11/483/prepub UR - http://www.biomedcentral.com/1471-2407/11/483/prepub ID - ref56 ER -