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Table 2 Using Independent HCC Studies to Validate HKU Gene Signature Identified at 0.05 Level

From: Clinicopathologic and gene expression parameters predict liver cancer prognosis

HKU Gene Signature in Normal Tissue
  Survival (7400 HKU Gene Signature)
  Overlapping Genes Enrichment p-value
Japanese Gene Signature 92 1.1E-9
Chinese-Belgium Gene Signature 133 3.1E-14
Asia HCC Metastases Gene Signature 144 2.0E-9
Singapore Gene Signature 19 2.4E-2
  Disease Free Survival (7661 HKU Gene Signature)
  Overlapping Genes Enrichment p-value
Japanese Gene Signature 96 1.8E-10
Chinese-Belgium Gene Signature 131 3.6E-12
Asia HCC Metastases Gene Signature 145 1.3E-8
Singapore Gene Signature 21 7.6E-3
HKU Gene Signature in Tumor Tissue
  Survival (5403 HKU Gene Signature)
  Overlapping Genes Enrichment p-value
Japanese Gene Signature 66 2.4E-6
Chinese-Belgium Gene Signature 142 5.5E-33
Asia HCC Metastases Gene Signature 97 1.2E-4
Singapore Gene Signature 19 4.9E-4
  Disease Free Survival (4377 HKU Gene Signature)
  Overlapping Genes Enrichment p-value
Japanese Gene Signature 58 9.1E-7
Chinese-Belgium Gene Signature 131 1.7E-35
Asia HCC Metastases Gene Signature 89 1.9E-6
Singapore Gene Signature 15 2.8E-3
  1. We selected genes associated with survival or disease-free survival using nominal p-value of 0.05.