From: Results of combined treatment of anaplastic thyroid carcinoma (ATC)
Number of patients (%) | 44 |
---|---|
Median age at diagnosis (years) | 65 (44-80) |
Gender | |
Female | 26 (59) |
Male | 18 (41) |
Female/male ratio | 1.4 |
Preexisting thyroid disease | |
Nodular goiter | 10 (22.7) |
Well-differentiated thyroid carcinoma | 8 (18.1) |
Clinical presentation | |
Enlarged thyroid mass | 38 (86.3) |
Signs of local compression (dyspnea, dysphagia, dysphonia, and cervical pain). | 32 (72.7) |
Weight loss | 12 (27.2) |
Clinical extent of disease | |
Local (T4 N0 M0) | 12 (27.2) |
Regional (T4 N1 M0) | 12 (27.2) |
Distant (T4 N0 M1, T4 N1 M1) | 20 (45.4) |
Histology | |
Giant cells | 19 (43.1) |
Spindle cells | 14 (31.8) |
Mixed pattern | 6 (13.6) |
Not available | 5 (11.3) |