Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

Table 6 Multivariate analyses for the development of HCC

1.Factors associated with HCC presence
	Multivariate analysis
Factor	Odds ratio	95% CI	p value
Age (≥ 45)	7.13	2.39-23.39	0.0004
G1613A and C1653T	7.19	1.42-56.0	0.016
2. Factors associated with future HCC emergence
	Multivariate analysis
Factor	Odds ratio	95% CI	p value
Age (≥ 45)	4.89	1.41-18.69	0.010
G1613A	4.73	1.11-21.69	0.035
3. Factors associated with the occurrence of HCC by
Multivariate Cox proportional hazard regression analysis
Factor	Odds ratio	95% CI	p value
Platelet (< 14 × 10⁴/μl)	6.28	1.66-30.11	0.0065
Factor	Odds ratio	95% CI	p value
Platelet (< 14 × 10⁴/μl)	6.28	1.66-30.11	0.0065

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