Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

Table 3 The prevalence of mutations in the samples

	Mutation frequency		Locations in open reading frames
	HCC group 1	non-HCC group1	Pol	X	C	S
G162A	42%	26%	357			177
A306G	9%	0%	405			225
A456G	10%	0%	455			275
C928T	37%	40%	613
C955T	11%	8%	622
A1032C	0%	7%	647
A1053G	33%	19%	654
A1126C	36%	41%	679
T1134C	36%	35%	681
T1323C	9%	16%	744
G1356A	7%	0%	755
C1485T	25%	27%	798	38
G1499A	37%	34%	803	42
G1511A	29%	23%	807	46
G1613A	38%	10%*	841	80
A1633G	5%	0%		87
C1653T	45%	19%*		94
G1727A	36%	51%		118
A1762T	74%	77%		130
G1764A	80%	84%		131
G2080A	13%	14%			89
C2444A	10%	0%	46		211
A2574G	24%	14%	90
C2586A	7%	0%	94
A2696G	8%	0%	130
G2783A	38%	33%	159
C2919T	5%	0%	205			24
C3026T	20%	16%	240			60
T3098C	19%	2%	84			264

ISSN: 1471-2407