Figure 2
From: Permissivity of the NCI-60 cancer cell lines to oncolytic Vaccinia Virus GLV-1h68
Expression of GFP in 74 cell lines infected with GLV-1h68. A) GFP protein expression data, ranked among the 74 cell lines according to infectivity index. With * are indicated the 46 cells previously analyzed by RT-PCR. B) Side by side comparison of 1/ΔCt (1/Ct GFP - Ct 18S) levels obtained by RT-PCR with GFP expression levels obtained by FACS showed similar pattern which is also highlighted by the scatter plot comparing GFP protein and RNA levels (R2 = 0.66) (C). D) Heat map of the 371 genes, identified by Student's t test (p 0.01) comparing 10 highest and 10 lowest GLV 1h68 permissive cell lines. The cells used for the comparison are indicated with a red bar.