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Table 1 Characteristics of patients (N = 225) and overall survival (OS)

From: TNFRSF1B +676 T>G polymorphism predicts survival of non-Small cell lung cancer patients treated with chemoradiotherapy

Variables

Patients No. (%)

Deaths No. (%)

MST (Months)

Log-rank P a

Age

    

   ≤62 years

111 (49.3)

72 (46.5)

25.6

0.117

   >62 years

114 (50.7)

83 (53.5)

21.1

 

Gender

    

   Female

102 (45.3)

65 (41.9)

26.7

0.036

   Male

123 (54.5)

90 (58.1)

22.3

 

Ethnicity

    

   White

162 (72.0)

117 (75.5)

23.5

0.827

   Non-White

63 (28.0)

38 (24.5)

22.3

 

Smokeb

    

   Ever

205 (91.5)

143 (92.9)

23.4

0.457

   Never

19 (8.5)

11 (7.1)

21.1

 

Histology

    

   Adenocarcinoma

79 (35.1)

48 (31.0)

27.3

0.092

   Squamous cell

71 (31.6)

51 (32.9)

23.2

 

   Others b

75 (33.3)

56 (36.1)

19.0

 

KPSc

    

   90-100

51 (25.4)

34 (22.7)

25.1

0.405

   80

118 (58.7)

90 (60.0)

22.1

 

   <80

32 (15.9)

26 (17.3)

21.1

 

Tumor stage c

    

   T0-2

127 (57.2)

81 (52.3)

26.9

0.010

   T3-4

95 (42.8)

74 (47.7)

19.2

 

Node status c

    

   N0-1

59 (26.7)

35 (22.6)

29.0

0.023

   N2-3

162 (73.3)

120 (77.4)

20.7

 

Chemotherapy

    

   Yes

163 (72.4)

113 (72.9)

26.9

0.407

   No

62 (27.6)

42 (27.1)

22.1

 

Radiotherapy dosed

    

   ≤63.0 Gy

115 (51.1)

77 (49.7)

22.7

0.706

   >63.0 Gy

110 (48.9)

78 (50.3)

25.1

 
  1. MST: median survival time; KPS: Karnofsky's performance scores
  2. a Log-rank test.
  3. b Others include large cell, undifferentiated and mixed-cell carcinomas.
  4. c Some missing data.
  5. dThe median radiotherapy dose is 63 Gy.