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Table 2 The average Mean Cell Survival (MCS) of the eleven body cavity lymphoma cell lines at different drug concentrations, expressed as the Q Area Under Curve values (QAUC).

From: Drug sensitivity patterns of HHV8 carrying body cavity lymphoma cell lines

   125 × dilution 25 × dilution 5 × dilution 1 × dilution   125 × dilution 25 × dilution 5 × dilution 1 × dilution
Effective drugs Chlorambucil Epirubicin
  MCS 14.8560 46.6236 80.8708 84.7608 MCS 19.2643 37.3816 63.5034 85.1459
  SD 15.3967 12.9966 21.0326 22.0111 SD 14.6115 16.3379 19.2617 26.7694
  QAUC 1,4285 7,1426 35,7129 178,5643 QAUC 0,0016 0,0079 0,0397 0,1985
  Paclitaxel Dactinomycin
  MCS 17.0131 45.1537 67.7781 89.5709 MCS 7.9351 36.0115 67.0155 86.7944
  SD 24.0155 49.5533 35.9258 22.0081 SD 8.4436 31.4395 26.8592 24.4412
  QAUC 0,0037 0,0185 0,0927 0,4636 QAUC 0,0267 0,1336 0,6679 3,3397
  Daunorubicin Docetaxel
  MCS 20.7690 27.3619 63.7950 87.2387 MCS 19.7376 21.9731 37.6060 59.5325
  SD 25.0224 24.1810 31.5421 23.0699 SD 21.0333 20.3415 21.1706 27.0225
  QAUC 0,0045 0,0226 0,1129 0,5643 QAUC 0,1923 0,9616 4,8081 24,0404
  Vinorelbine Vinblastin
  MCS 18.1346 20.5045 40.0830 53.0230 MCS 26.8433 40.9968 67.9391 81.0989
  SD 16.8776 21.5082 22.6266 26.5102 SD 32.9835 31.9132 33.5183 17.2183
  QAUC 0,0096 0,0481 0,2404 1,2020 QAUC 0,0281 0,1404 0,7020 3,5100
  Asparaginase Fluorouracil
  MCS 33.4151 62.3275 90.6113 94.4347 MCS 41.1156 58.9125 70.3122 83.0342
  SD 25.9953 34.9567 26.1363 23.3606 SD 19.1314 27.2339 23.4010 19.8986
  QAUC 0,0903 0,4517 2,2587 11,2937 QAUC 0,3463 1,7313 8,6566 43,2831
  Etoposide Doxorubicin
  MCS 30.6138 50.2125 64.2707 74.6943 MCS 29.0927 66.8651 77.2076 80.7702
  SD 20.8709 23.8410 23.6330 19.0535 SD 19.1960 25.0111 26.0959 27.3229
  QAUC 0,0433 0,2164 1,0818 5,4091 QAUC 0,0009 0,0044 0,0219 0,1095
  Gemcitabin Methotrexate
  MCS 31.4369 45.9785 58.4073 67.9991 MCS 47.1542 44.9205 70.0761 84.2659
  SD 33.0357 38.5124 37.0529 36.6568 SD 22.4628 21.6895 25.4751 25.4385
  QAUC 0,0495 0,2473 1,2367 6,1837 QAUC 0,0192 0,0962 0,4810 2,4050
  Vincristine Topotecan
  MCS 43.8400 69.1932 80.2086 81.6665 MCS 41.8048 75.3319 84.1050 90.7907
  SD 34.7208 35.8971 29.9816 32.6203 SD 16.4675 24.5366 25.2812 25.3696
  QAUC 0,3091 1,5455 7,7273 38,6364 QAUC 0,0215 0,1077 0,5385 2,6926
Non-effective drugs Bortezomib Bleomycin
  MCS 79.4105 66.8656 68.2865 64.8357 MCS 60.3729 69.3422 76.5090 80.8431
  SD 25.4732 25.6668 28.0206 24.9547 SD 16.7323 18.8710 22.7197 16.8950
  QAUC 0,0222 0,1110 0,5548 2,7739 QAUC 0,0173 0,0866 0,4330 2,1650
  Cladribine 6-mercaptopurin
  MCS 81.0033 82.0998 84.1061 92.0852 MCS 74.0197 87.8677 97.1334 98.2332
  SD 21.2666 22.0174 20.1630 21.3224 SD 28.3769 23.3376 30.0858 25.3860
  QAUC 0,0846 0,4231 2,1156 10,5778 QAUC 0,2886 1,4429 7,2146 36,0729
  Oxaliplatin Cytarabine
  MCS 87.0156 89.3148 82.6868 86.8853 MCS 69.9787 77.2199 83.5057 89.0542
  SD 30.3307 26.7413 24.1939 25.6311 SD 31.2151 36.2648 38.6377 32.5155
  QAUC 0,0089 0,0444 0,2218 1,1090 QAUC 0,0433 0,2164 1,0818 5,4091
  Prednisolone Mitomycin
  MCS 98.9838 99.8113 95.6985 92.9011 MCS 73.4043 79.2375 80.0565 79.4133
  SD 12.7979 15.5728 14.2013 14.0330 SD 28.5533 19.7620 18.7334 19.3133
  QAUC 0,2886 1,4428 7,2139 36,0693 QAUC 0,0714 0,3571 1,7857 8,9286
  Hydroxyurea Carboplatin
  MCS 88.8788 86.3322 97.5959 98.8578 MCS 113.3868 103.2988 113.4341 110.1786
  SD 21.5473 19.8568 17.5610 18.7218 SD 39.2983 27.4344 43.5238 38.6427
  QAUC 0,0381 0,1904 0,9522 4,7611 QAUC 0,0007 0,0036 0,0180 0,0902
  Fludarabine      
  MCS 67.0129 76.1851 79.2040 95.8649      
  SD 43.0343 35.3340 37.6906 19.6811      
  QAUC 0,4329 2,1645 10,8223 54,1117