Table 2 The average Mean Cell Survival (MCS) of the eleven body cavity lymphoma cell lines at different drug concentrations, expressed as the Q Area Under Curve values (QAUC).

Effective drugs

Chlorambucil

Epirubicin

MCS

14.8560

46.6236

80.8708

84.7608

MCS

19.2643

37.3816

63.5034

85.1459

SD

15.3967

12.9966

21.0326

22.0111

SD

14.6115

16.3379

19.2617

26.7694

QAUC

1,4285

7,1426

35,7129

178,5643

QAUC

0,0016

0,0079

0,0397

0,1985

Paclitaxel

Dactinomycin

MCS

17.0131

45.1537

67.7781

89.5709

MCS

7.9351

36.0115

67.0155

86.7944

SD

24.0155

49.5533

35.9258

22.0081

SD

8.4436

31.4395

26.8592

24.4412

QAUC

0,0037

0,0185

0,0927

0,4636

QAUC

0,0267

0,1336

0,6679

3,3397

Daunorubicin

Docetaxel

MCS

20.7690

27.3619

63.7950

87.2387

MCS

19.7376

21.9731

37.6060

59.5325

SD

25.0224

24.1810

31.5421

23.0699

SD

21.0333

20.3415

21.1706

27.0225

QAUC

0,0045

0,0226

0,1129

0,5643

QAUC

0,1923

0,9616

4,8081

24,0404

Vinorelbine

Vinblastin

MCS

18.1346

20.5045

40.0830

53.0230

MCS

26.8433

40.9968

67.9391

81.0989

SD

16.8776

21.5082

22.6266

26.5102

SD

32.9835

31.9132

33.5183

17.2183

QAUC

0,0096

0,0481

0,2404

1,2020

QAUC

0,0281

0,1404

0,7020

3,5100

Asparaginase

Fluorouracil

MCS

33.4151

62.3275

90.6113

94.4347

MCS

41.1156

58.9125

70.3122

83.0342

SD

25.9953

34.9567

26.1363

23.3606

SD

19.1314

27.2339

23.4010

19.8986

QAUC

0,0903

0,4517

2,2587

11,2937

QAUC

0,3463

1,7313

8,6566

43,2831

Etoposide

Doxorubicin

MCS

30.6138

50.2125

64.2707

74.6943

MCS

29.0927

66.8651

77.2076

80.7702

SD

20.8709

23.8410

23.6330

19.0535

SD

19.1960

25.0111

26.0959

27.3229

QAUC

0,0433

0,2164

1,0818

5,4091

QAUC

0,0009

0,0044

0,0219

0,1095

Gemcitabin

Methotrexate

MCS

31.4369

45.9785

58.4073

67.9991

MCS

47.1542

44.9205

70.0761

84.2659

SD

33.0357

38.5124

37.0529

36.6568

SD

22.4628

21.6895

25.4751

25.4385

QAUC

0,0495

0,2473

1,2367

6,1837

QAUC

0,0192

0,0962

0,4810

2,4050

Vincristine

Topotecan

MCS

43.8400

69.1932

80.2086

81.6665

MCS

41.8048

75.3319

84.1050

90.7907

SD

34.7208

35.8971

29.9816

32.6203

SD

16.4675

24.5366

25.2812

25.3696

QAUC

0,3091

1,5455

7,7273

38,6364

QAUC

0,0215

0,1077

0,5385

2,6926

Non-effective drugs

Bortezomib

Bleomycin

MCS

79.4105

66.8656

68.2865

64.8357

MCS

60.3729

69.3422

76.5090

80.8431

SD

25.4732

25.6668

28.0206

24.9547

SD

16.7323

18.8710

22.7197

16.8950

QAUC

0,0222

0,1110

0,5548

2,7739

QAUC

0,0173

0,0866

0,4330

2,1650

Cladribine

6-mercaptopurin

MCS

81.0033

82.0998

84.1061

92.0852

MCS

74.0197

87.8677

97.1334

98.2332

SD

21.2666

22.0174

20.1630

21.3224

SD

28.3769

23.3376

30.0858

25.3860

QAUC

0,0846

0,4231

2,1156

10,5778

QAUC

0,2886

1,4429

7,2146

36,0729

Oxaliplatin

Cytarabine

MCS

87.0156

89.3148

82.6868

86.8853

MCS

69.9787

77.2199

83.5057

89.0542

SD

30.3307

26.7413

24.1939

25.6311

SD

31.2151

36.2648

38.6377

32.5155

QAUC

0,0089

0,0444

0,2218

1,1090

QAUC

0,0433

0,2164

1,0818

5,4091

Prednisolone

Mitomycin

MCS

98.9838

99.8113

95.6985

92.9011

MCS

73.4043

79.2375

80.0565

79.4133

SD

12.7979

15.5728

14.2013

14.0330

SD

28.5533

19.7620

18.7334

19.3133

QAUC

0,2886

1,4428

7,2139

36,0693

QAUC

0,0714

0,3571

1,7857

8,9286

Hydroxyurea

Carboplatin

MCS

88.8788

86.3322

97.5959

98.8578

MCS

113.3868

103.2988

113.4341

110.1786

SD

21.5473

19.8568

17.5610

18.7218

SD

39.2983

27.4344

43.5238

38.6427

QAUC

0,0381

0,1904

0,9522

4,7611

QAUC

0,0007

0,0036

0,0180

0,0902

Fludarabine

MCS

67.0129

76.1851

79.2040

95.8649

SD

43.0343

35.3340

37.6906

19.6811

QAUC

0,4329

2,1645

10,8223

54,1117